This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Sodium chlorite
DrugBank Accession Number
DB13210
Background

Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug 1,2.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 90.442
Monoisotopic: 89.948451626
Chemical Formula
ClNaO2
Synonyms
Not Available

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
D.PRO Pack SolidPowder23 g/100gTopicalPure O22021-04-17Not applicableUS flag
Defender SignaturePowder23 g/100gTopicalPure O22021-04-17Not applicableUS flag
DefenderstickLiquid5 g/100gTopicalPure O22021-04-17Not applicableUS flag
Doctor GuardStickLiquid5 g/100gTopicalPure O22020-04-01Not applicableUS flag
Dr. Guard Pack SolidLiquid5 g/100gTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag
Dr. Guard Pack SolidPowder10 g/100gTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag
Dr. Guard Special Car EditionLiquid5 g/100gTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag
Dr. Guard Special Car Edition Refill StickLiquid5 g/100gTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag
Dr. Guard StickLiquid5 g/100gTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag
EasystickLiquid5 g/100gTopicalYESUNG GLOBAL.Co.,Ltd2021-01-27Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Av-1000Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Av100Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
B100Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Bt100sSodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Cloon StickSodium chlorite (3 g/100g) + Citric acid monohydrate (5 g/100g)LiquidTopicalSejin E&P Co., Ltd.2022-01-15Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Av-1000Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Av100Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
B100Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Bt100sSodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g)PowderTopicalSejin E&P Co., Ltd.2020-05-02Not applicableUS flag
Cloon StickSodium chlorite (3 g/100g) + Citric acid monohydrate (5 g/100g)LiquidTopicalSejin E&P Co., Ltd.2022-01-15Not applicableUS flag
D.PRO Pack SolidSodium chlorite (23 g/100g)PowderTopicalPure O22021-04-17Not applicableUS flag
Defender SignatureSodium chlorite (23 g/100g)PowderTopicalPure O22021-04-17Not applicableUS flag
DefenderstickSodium chlorite (5 g/100g)LiquidTopicalPure O22021-04-17Not applicableUS flag
Doctor GuardStickSodium chlorite (5 g/100g)LiquidTopicalPure O22020-04-01Not applicableUS flag
Dr. Guard Pack SolidSodium chlorite (10 g/100g)PowderTopicalJBK FORMS Co Ltd2021-11-04Not applicableUS flag

Categories

ATC Codes
D03AX11 — Sodium chlorite
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as alkali metal chlorites. These are inorganic compounds in which the largest oxoanion is chlorite, and in which the heaviest atom not in an oxoanion is an alkali metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Alkali metal oxoanionic compounds
Sub Class
Alkali metal chlorites
Direct Parent
Alkali metal chlorites
Alternative Parents
Inorganic sodium salts / Inorganic oxides
Substituents
Alkali metal chlorite / Inorganic oxide / Inorganic salt / Inorganic sodium salt
Molecular Framework
Not Available
External Descriptors
inorganic sodium salt, chlorite salt (CHEBI:78667)
Affected organisms
Not Available

Chemical Identifiers

UNII
G538EBV4VF
CAS number
7758-19-2
InChI Key
UKLNMMHNWFDKNT-UHFFFAOYSA-M
InChI
InChI=1S/ClHO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1
IUPAC Name
sodium chlorite
SMILES
[Na+].[O-][Cl]=O

References

General References
  1. Shinada K, Ueno M, Konishi C, Takehara S, Yokoyama S, Zaitsu T, Ohnuki M, Wright FA, Kawaguchi Y: Effects of a mouthwash with chlorine dioxide on oral malodor and salivary bacteria: a randomized placebo-controlled 7-day trial. Trials. 2010 Feb 12;11:14. doi: 10.1186/1745-6215-11-14. [Article]
  2. FDA - CFR - Code of Federal Regulations Title 21 [Link]
KEGG Compound
C19523
ChemSpider
22860
RxNav
992920
ChEBI
78667
ChEMBL
CHEMBL1887585
Wikipedia
Sodium_chlorite

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
PowderTopical
LiquidTopical
PowderTopical10 g/100g
LiquidTopical5 g/100g
PowderTopical5 g/100g
TabletTopical30 g/100g
PowderTopical23 g/100g
LiquidTopical4.6 g/100mL
PowderTopical16 g/100g
LiquidOral
StickTopical20 g/100g
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility453.0 mg/mLALOGPS
logP-0.91ALOGPS
logP0.18ChemAxon
logS0.7ALOGPS
pKa (Strongest Acidic)-4.6ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area40.13 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity9.02 m3·mol-1ChemAxon
Polarizability3.91 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at June 23, 2017 20:37 / Updated at September 28, 2021 21:54