This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Sodium chlorite
- DrugBank Accession Number
- DB13210
- Background
Used as an agent for cleaning drinking water. It is also used as an additive in products like toothpaste and mouthwash. Acidified sodium chlorite was approved by the U.S. Food and Drug Administration as of 2004, as an anti-microbial agent which is non-toxic, but not as a drug 1,2.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Sodium chlorite (DB13210)
- Weight
- Average: 90.442
Monoisotopic: 89.948451626 - Chemical Formula
- ClNaO2
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image D.PRO Pack Solid Powder 23 g/100g Topical Pure O2 2021-04-17 Not applicable US 
Defender Signature Powder 23 g/100g Topical Pure O2 2021-04-17 Not applicable US Defenderstick Liquid 5 g/100g Topical Pure O2 2021-04-17 Not applicable US Doctor GuardStick Liquid 5 g/100g Topical Pure O2 2020-04-01 Not applicable US Dr. Guard Pack Solid Liquid 5 g/100g Topical JBK FORMS Co Ltd 2021-11-04 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Av-1000 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Av100 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US B100 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Bt100s Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Cloon Stick Sodium chlorite (3 g/100g) + Citric acid monohydrate (5 g/100g) Liquid Topical Sejin E&P Co., Ltd. 2022-01-15 Not applicable US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Av-1000 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Av100 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US B100 Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Bt100s Sodium chlorite (0.05 g/100g) + Citric acid monohydrate (0.06 g/100g) Powder Topical Sejin E&P Co., Ltd. 2020-05-02 Not applicable US Cloon Stick Sodium chlorite (3 g/100g) + Citric acid monohydrate (5 g/100g) Liquid Topical Sejin E&P Co., Ltd. 2022-01-15 Not applicable US
Categories
- ATC Codes
- D03AX11 — Sodium chlorite
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as alkali metal chlorites. These are inorganic compounds in which the largest oxoanion is chlorite, and in which the heaviest atom not in an oxoanion is an alkali metal.
- Kingdom
- Inorganic compounds
- Super Class
- Mixed metal/non-metal compounds
- Class
- Alkali metal oxoanionic compounds
- Sub Class
- Alkali metal chlorites
- Direct Parent
- Alkali metal chlorites
- Alternative Parents
- Inorganic sodium salts / Inorganic oxides
- Substituents
- Alkali metal chlorite / Inorganic oxide / Inorganic salt / Inorganic sodium salt
- Molecular Framework
- Not Available
- External Descriptors
- inorganic sodium salt, chlorite salt (CHEBI:78667)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- G538EBV4VF
- CAS number
- 7758-19-2
- InChI Key
- UKLNMMHNWFDKNT-UHFFFAOYSA-M
- InChI
- InChI=1S/ClHO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1
- IUPAC Name
- sodium chlorite
- SMILES
- [Na+].[O-][Cl]=O
References
- General References
- Shinada K, Ueno M, Konishi C, Takehara S, Yokoyama S, Zaitsu T, Ohnuki M, Wright FA, Kawaguchi Y: Effects of a mouthwash with chlorine dioxide on oral malodor and salivary bacteria: a randomized placebo-controlled 7-day trial. Trials. 2010 Feb 12;11:14. doi: 10.1186/1745-6215-11-14. [Article]
- FDA - CFR - Code of Federal Regulations Title 21 [Link]
- External Links
- KEGG Compound
- C19523
- ChemSpider
- 22860
- 992920
- ChEBI
- 78667
- ChEMBL
- CHEMBL1887585
- Wikipedia
- Sodium_chlorite
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Powder Topical Liquid Topical Powder Topical 10 g/100g Liquid Topical 5 g/100g Powder Topical 5 g/100g Tablet Topical 30 g/100g Powder Topical 23 g/100g Liquid Topical 4.6 g/100mL Powder Topical 16 g/100g Liquid Oral Stick Topical 20 g/100g - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 453.0 mg/mL ALOGPS logP -0.91 ALOGPS logP 0.18 Chemaxon logS 0.7 ALOGPS pKa (Strongest Acidic) -4.6 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 40.13 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 9.02 m3·mol-1 Chemaxon Polarizability 3.91 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 107.13203 predictedDeepCCS 1.0 (2019) [M+H]+ 108.91821 predictedDeepCCS 1.0 (2019) [M+Na]+ 116.00843 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:37 / Updated at September 28, 2021 21:54