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Indapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive
Mixtures: Triplixam 10 mg/2,5 mg/5 mg Filmtabletten, Triplixam 5 mg/1,25 mg/10 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedIt is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy
Mixtures: GRAVIDINONA 2 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedFor many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. … Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919.
Mixtures: B Plus C 300 mg, Stress B With 1000 Mg Vitamin CCategories: Vitamin B ComplexErdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigational[L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy … with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing chemotherapy, including within 12
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: BALVERSA 5 MG FİLM KAPLI TABLET, 28 ADET, BALVERSA 3 MG FİLM KAPLI TABLET, 56 ADETGadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigational[A263131] It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). … due to a decreased tendency of gadolinium dechelation.
Categories: Compounds used in a research, industrial, or household settingSynonyms: [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4N1,N4,N7,N10)tetraacetato(3−)]gadoliniumGuanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesProducts: ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 7 TABLET, ARİSLOW ER 1 MG UZATILMIŞ SALIMLI TABLET, 28 TABLETRemlarsen
go.drugbank.com/drugs/DB19131InvestigationalRemlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids).
Synonyms: -cholest-5-en-3-yloxy)hexyl)oxy)-2-hydroxypropyl hydrogen phosphate), complex with rna ((2'-deoxy-2'-fluoro)u-a-g-(2'-deoxy-2'-fluoro)c-a-(2'-deoxy-2'-fluoro)c-(2'-de, Rna, (am-am-cm-a-cm-um-g-um-um-um-a-cm-a-a-a-um-g-g-um-cm-cm-um-a), 3'-(3-((6-((3.beta.)Darunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.
Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, FURTHAS®R TABLETAS RECUBIERTASCategories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Zilucoplan
go.drugbank.com/drugs/DB15636ApprovedInvestigationalZilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses.
Synonyms: .-(2-(((4S)-4-CARBOXY-1-OXO-4-(1-OXOHEXADECYL)BUTYL)AMINO)ETHYL)-.OMEGA.-HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA., N2-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA.-ASPARTYL-N-METHYL-L-.ALPHA.-ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA.Products: Zılbrysq 16,6 mg/0,416 mL SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (7 Adet), Zılbrysq 23 mg/0,574 mL SC Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (7 Adet)Glimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalIt is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs. … Type 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular
Mixtures: AMARYL®M 1 MG/ 500 MG, DUERID 30/2 MG TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates