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Darolutamide
go.drugbank.com/drugs/DB12941ApprovedInvestigational[A189063] Though prior treatment for prostate cancer has been successful for these patients, the cancer eventually progresses to become resistant to existing therapies. … The goal of treatment with darolutamide is to delay the progression of prostate cancer to metastatic disease, increasing quality of life and life expectancy for those with advanced prostate cancer.
Influenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15620ApprovedInvestigationalVaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen … that it was previously exposed to.
Mixtures: Influvac Tetra, suspension for injection in pre-filled syringe, Vaxigrip Tetra, Suspension for Injection in Pre-filled SyringePhenacemide
go.drugbank.com/drugs/DB01121ApprovedPhenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.
Solriamfetol
go.drugbank.com/drugs/DB14754ApprovedInvestigationalwith narcolepsy or obstructive sleep apnea[FDA Label]. … Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated
Categories: Psychostimulants, Agents Used for ADHD and NootropicsDrinabant
go.drugbank.com/drugs/DB05750InvestigationalAVE-1625 is also being developed for the treatment of Alzheimer disease. … AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant.
Aceclidine
go.drugbank.com/drugs/DB13262Approved, and lens anterior displacement, leading to reduced risk of retina or vitreous tractions. … [A274283] As compared to less selective miotics, like [pilocarpine], aceclidine's relative stimulation of the ciliary muscle is significantly less and, as such, induces far less myopic shift, lens thickening
Pergolide
go.drugbank.com/drugs/DB01186ApprovedVet approvedWithdrawnPergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. … While the use of pergolide in humans is still approved in only some countries, pergolide is mainly used for veterinary purposes.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Heterocyclic Compounds with 4 or More RingsAlefacept
go.drugbank.com/drugs/DB00092ApprovedWithdrawnProduced by CHO cells, mW is 91.4 kD. … Immunosuppressive dimeric fusion protein that consists of the extracellular CD2-binding portion of the human leukocyte function antigen-3 (LFA-3) linked to the Fc (hinge, CH2 and CH3 domains) portion of
Tibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of osteoporosis [L1876]. … Tibolone has been to have anti-resorptive effects on bone [L1874].
Synonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneDexfenfluramine
go.drugbank.com/drugs/DB01191ApprovedIllicitWithdrawnFor a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome