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Displaying results 3021 - 3030 of 10000 in total
  1. Target

    Monocarboxylate transporter 10

    go.drugbank.com/bio_entities/BE0003654
    TransporterHumans

    Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (PubMed:18337592

    Polypeptides: Monocarboxylate transporter 10Synonyms: MCT 10, Solute carrier family 16 member 10
  2. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate. … For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats.

    Synonyms: Vitamin B5, D-pantothenic acidMixtures: B Plus C 300 mg, Stress B With 1000 Mg Vitamin C
  3. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … Marketed as the brand name product Apidra, insulin glulisine begins to exert its effects within 15 minutes of subcutaneous administration, while peak levels occur 30 to 90 minutes after administration.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: APIDRA 100 U/ML SOLOSTAR ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 ADET, APIDRA OPTIPEN 100 IU/ML SC KULLANIMI İÇİN ENJEKSİYONLUK ÇÖZELTİ, 5 ADET
  4. Drug

    Doravirine

    go.drugbank.com/drugs/DB12301
    ApprovedInvestigational

    [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). … treatments available for the management of HIV-1 infection.

    Categories: Heterocyclic Compounds, 1-Ring, Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase InhibitorProducts: PİFELTRO 100 MG FİLM KAPLI TABLET, 30 ADET
  5. Drug

    Pirfenidone

    go.drugbank.com/drugs/DB04951
    ApprovedInvestigational

    [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form … Pirfenidone is a synthetic pyridone drug.

    Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: ESBRİET 267 MG FİLM KAPLI TABLET, 180, PİRFA 600 MG FİLM KAPLI TABLET, 120 ADET
  6. Drug

    Methoxy polyethylene glycol-epoetin beta

    go.drugbank.com/drugs/DB09107
    ApprovedInvestigational

    Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.

    Categories: Compounds used in a research, industrial, or household setting, Blood and Blood Forming OrgansProducts: MIRCERA 50 UG/0.3 ML, MIRCERA® SOLUCION INYECTABLE JERINGA PRELLENADA 50 MCG / 0.3 ML
  7. Drug

    Chlorprothixene

    go.drugbank.com/drugs/DB01239
    ApprovedInvestigationalWithdrawn

    Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. … Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: Truxal 50 mg - Filmtabletten, Truxal 15 mg - Filmtabletten
  8. Drug

    Spiramycin

    go.drugbank.com/drugs/DB06145
    ApprovedInvestigationalWithdrawn

    Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in oral formulations since 1955, and parenteral formulations since 1987. … Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types

    Synonyms: Spiramycin 1, Foromacidin AMixtures: METİRASİN 1,5 MIU/250 MG FİLM KAPLI TABLET, 10 ADET, METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET
  9. Drug

    Valganciclovir

    go.drugbank.com/drugs/DB01610
    ApprovedInvestigational

    As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.

    Categories: Heterocyclic Compounds, 2-Ring, Ganciclovir and prodrugProducts: AVALCEPT 50 MG / ML ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 100 ML, Valcyte 50 mg/ml - Pulver zur Herstellung einer Lösung zum Einnehmen
  10. Drug

    Miltefosine

    go.drugbank.com/drugs/DB09031
    ApprovedInvestigational

    It can be administered topically or orally and is only indicated in patients aged 12 years or older. … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease.

    Synonyms: hexadecyl 2-(trimethylazaniumyl)ethyl phosphateCategories: P-glycoprotein substrates, Agents Against Leishmaniasis and Trypanosomiasis