Monocarboxylate transporter 10

BE0003654ProteinHumansSLC16A10

Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed:11827462, PubMed:18337592, PubMed:28754537). It is acted on by 36 drugs in DrugBank.

Gene name
SLC16A10
UniProtKB entry
Q8TF71Swiss-Prot
Cellular location
Cell membrane
Residues / weight
515 residues · 55,492 Da
Also known as
Aromatic amino acid transporter 1 · MCT 10 · MCT10 · Solute carrier family 16 member 10 · T-type amino acid transporter 1

Resolves to

Protein
UniProtQ8TF71UniProt nameMOT10_HUMAN
Gene
HGNCHGNC:17027NCBI Gene117247GenBank18640047GeneCardsSLC16A10
Pharmacology
KEGGhsa:117247
Structure
PDB9GSZPDB9HHQ
Drugs

What you can answer from here — as of September 07, 2019

36DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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54+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Monocarboxylate transporter 10, how selective are they, and which programs against it are still in active trials?

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