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Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalIt belongs to the same drug class as [Roflumilast] and [Crisaborole].[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases.
Synonyms: N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamideMixtures: OTEZLA 10 MG. 20 MG Y 30 MG, OTEZLA 10 MG. 20 MG Y 30 MGNifuroxazide
go.drugbank.com/drugs/DB13855InvestigationalMixtures: METRONIDAZOL/NIFUROXAZIDA 300 MG/100 MG., METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSIONCategories: Heterocyclic Compounds, 1-RingRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalIn a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months … Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoperosis in postmenopausal women at high risk of fracture and patients who have failed in other treatments or are intolerant
Products: EVENİTY 105 MG/1,17 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 MLOxybuprocaine
go.drugbank.com/drugs/DB00892ApprovedInvestigationalOxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology.
Mixtures: AMIGDAL-B®, BUCALIV® TABLETA MASTICABLECategories: Antihistamines, Anesthetics, Etc.Spiramycin
go.drugbank.com/drugs/DB06145ApprovedInvestigationalWithdrawnSpiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in oral formulations since 1955, and parenteral formulations since 1987. … Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types
Synonyms: Spiramycin 1, Foromacidin AMixtures: METİRASİN 1,5 MIU/250 MG FİLM KAPLI TABLET, 10 ADET, METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADETArgatroban
go.drugbank.com/drugs/DB00278ApprovedInvestigationalArgatroban is a direct, selective thrombin inhibitor. … The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous coronary
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Argatra 1 mg/ml Infusionslösung, Argatroban Accord 1 mg/ml InfusionslösungTetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate
go.drugbank.com/drugs/DB14106ApprovedInvestigationalTetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]
Synonyms: Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborate, Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborateProducts: MON.MIBI KIT, 1.0 MG/FLAKON IV ENJEKSİYON İÇİN STERİL/APİROJEN LİYOFİLİZE TOZ, 5 ADET, MIBITEC 1 mg Kit für ein radioaktives ArzneimittelSelinexor
go.drugbank.com/drugs/DB11942ApprovedInvestigational[L7123] Selinexor was also granted accelerated approval for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) that have gone through at least 2 lines of … Selinexor is a first-in-class selective inhibitor of nuclear transport (SINE) compound.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexpovio 20 mg Film Kaplı Tablet, 8 TABLET, Nexpovio 20 mg Film Kaplı Tablet, 12 TABLETSelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalNF-1 is considered rare, with an estimated incidence of 1/3000 individuals. … [A193611] "The novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform
Categories: Mitogen-Activated Protein Kinase Kinase 1 Inhibitors, P-glycoprotein substratesProducts: Koselugo Hard Capsules 10 mg, Koselugo Hard Capsules 25 mgLanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalIt is approved in several countries worldwide, including the United Kingdom, Australia, and Canada. Lanreotide was first approved for use in the United States by the FDA on August 30, 2007. … This drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: SOMATULINE ® AUTOGEL ® 60 MG, SOMATULINE AUTOGEL 120 MG/0,5 ML UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ŞIRINGA, 1 ADET