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Displaying results 3031 - 3040 of 10000 in total
  1. Drug

    Tigilanol tiglate

    go.drugbank.com/drugs/DB18800
    Investigational

    Synonyms: (4s,5s,6r,7s,8r,9r,10s,11r,12r,13s,14r)-12-(2e)-2-methyl-2-enoatyl-13((2s)-2-methylbutyroyl)-6,7-epoxy-4,5,9,12,13,20-hexahydroxy-1-tigliaen-3-one, 12-tigloyl-13-(2-methylbutanoyl)-6,7-epoxy-4,5,9,12,13,20-hexahydroxy-1-tiglian-3-one
  2. Drug

    Seclidemstat

    go.drugbank.com/drugs/DB17117
    Investigational

    Synonyms: Benzoic acid, 3-((4-methyl-1-piperazinyl)sulfonyl)-, (2e)-2-(1-(5-chloro-2-hydroxyphenyl)ethylidene)hydrazide, N'-[(1E)-1-(5-chloro-2-hydroxyphenyl)ethylidene]- 3-(4-methylpiperazine-1-sulfonyl)benzohydrazideCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Synonyms: 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine, 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index
  4. Drug

    D-Leucine

    go.drugbank.com/drugs/DB01746
    Experimental

    An essential branched-chain amino acid important for hemoglobin formation. [PubChem]

    Synonyms: (2R)-2-amino-4-methylpentanoic acid, D-2-Amino-4-methylvaleric acid
  5. Drug

    AV-101

    go.drugbank.com/drugs/DB12878
    Investigational

    AV-101 has been used in trials studying the treatment of Neuropathic Pain.

    Synonyms: (2S)-2-amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid, L-4-CL-KYN
  6. Drug

    KAND567

    go.drugbank.com/drugs/DB16511
    Investigational

    KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation[L32908]. … Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as a treatment for those with the illness[L32908].

    Synonyms: 1-Pentanol, 2-[[2-aMino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyriMidin-7-yl]aMino]-4-Methyl-, (2R)-
  7. Drug

    Pittsburgh Compound B

    go.drugbank.com/drugs/DB15161
    Investigational

    Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole, (N-methyl-(11C))2-(4'-methylaminophenyl)-6-hydroxybenzothiazole
  8. Drug

    N-Methylmesoporphyrin containing copper

    go.drugbank.com/drugs/DB02188
    Experimental

    Synonyms: 3-[18-(2-Carboxyethyl)-7,12-diethyl-3,8,13,17,23-pentamethylporphyrin-21-id-2-yl]propanoic acid;copper(1+), N-Methylmesoporphyrin containing copper
  9. Drug

    Paclitaxel trevatide

    go.drugbank.com/drugs/DB06171
    Investigational

    Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.

    Synonyms: [a-N-(2'succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Arg-Asn-Asn-Phe-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr
  10. Drug

    IMT-288

    go.drugbank.com/drugs/DB19068
    Investigational

    IMT-288 is under investigation in clinical trial NCT01730638 (Immunotep for Patients With Medullary Thyroid Carcinoma.).

    Synonyms: (4R)-5-(((1R)-1-CARBAMOYL-5-((2-((4-(2-(1H-IMIDAZOL-5-YL)ETHYLAMINO)-4-OXO-BUTANOYL)AMINO)ACETYL)AMINO)PENTYL)AMINO)-4-(((2R)-2-(((2R)-3-(4-HYDROXYPHENYL)-2-((2-(4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAZACYCLODODEC, -GLUTAMYL-N6-(N-(4-((2-(1H-IMIDAZOL-4-YL)ETHYL)AMINO)-1,4-DIOXOBUTYL)GLYCY