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Displaying results 3061 - 3070 of 7284 in total
  1. Drug

    Levamlodipine

    go.drugbank.com/drugs/DB09237
    ApprovedInvestigational

    [A188940] Levamlodipine was granted FDA approval on 19 December 2019.[L10833] … [L10833] This medication was first marketed in Russia and India before being granted FDA approval.

  2. Drug

    Imdevimab

    go.drugbank.com/drugs/DB15940
    ApprovedInvestigational

    Imdevimab is a monoclonal antibody combined with [casirivimab] in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. … Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved by the FDA.

  3. Drug

    Normethadone

    go.drugbank.com/drugs/DB11609
    ApprovedIllicit

    Normethadone is used as an opioid antitussive in combination with DB11610. It is marketed in Canada by Valeant under the tradename Cophylac.

  4. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

    go.drugbank.com/bio_entities/BE0000037
    TargetHumans

    Essential for the catalytic activity and assembly of complex I (PubMed:22499348) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-23kD
  5. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

    go.drugbank.com/bio_entities/BE0000093
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-13kD-A
  6. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

    go.drugbank.com/bio_entities/BE0000307
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:17275378) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-20kD
  7. Drug

    Imnopitant

    go.drugbank.com/drugs/DB21456
    Experimental

    Imnopitant has a monoisotopic molecular weight of 550.22 Da. … Imnopitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1​ (substance P) receptor antagonist.

  8. Drug

    Libvatrep

    go.drugbank.com/drugs/DB21488
    Experimental

    Libvatrep has a monoisotopic molecular weight of 305.12 Da. … Libvatrep is a small molecule drug. The usage of the INN stem '-vatrep' in the name indicates that Libvatrep is a transient receptor potential vanilloid (TRPV) antagonist.

  9. Drug

    Pramiverine

    go.drugbank.com/drugs/DB19588
    Experimental

    Pramiverine has a monoisotopic molecular weight of 293.21 Da. … Pramiverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Pramiverine is a spasmolytic with a papaverine-like action.

  10. Drug

    Mofegiline

    go.drugbank.com/drugs/DB19621
    Experimental

    Mofegiline has a monoisotopic molecular weight of 197.1 Da. … Mofegiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Mofegiline is a monoamine oxydase (MAO)-inhibitor type B.

    Categories: Amine Oxidase (Copper-Containing), antagonists & inhibitors