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COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalDC-based vaccines are currently used in cancer therapeutics, and are being tested for COVID-19. … The rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response.
Yellow fever vaccine
go.drugbank.com/drugs/DB10805ApprovedInvestigationalYellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like i...
Elasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalThe Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavir...
Phenelzine
go.drugbank.com/drugs/DB00780ApprovedInvestigationalPhenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA ap...
Categories: Cytochrome P-450 CYP2E1 Inducers, Cytochrome P-450 CYP2C19 InhibitorsAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigationalAnti-neutrophil cytoplasmic (auto)antibody (ANCA)-associated vasculitis (AAV) is a rare (estimated incidence of 3 cases per 100,000 per year) form of "pauci-immune" systemic small-vessel vasculitis typified by the presence of ANCAs in th...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesTheobromine
go.drugbank.com/drugs/DB01412InvestigationalTheobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophyl...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesViral Macrophage-Inflammatory Protein
go.drugbank.com/drugs/DB15748ExperimentalViral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus...
DA-6886
go.drugbank.com/drugs/DB12853InvestigationalDA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.
Methyl-D9-choline
go.drugbank.com/drugs/DB12628InvestigationalMethyl-D9-choline is under investigation in clinical trial NCT01807910 (ER Stress in NAFLD).