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Glimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalType 2 diabetes is a metabolic disorder with increasing prevalences worldwide; it is characterized by insulin resistance in accordance with progressive β cell failure and long-term microvascular and macrovascular … [A177703] It is effective in reducing fasting plasma glucose, postprandial glucose, and glycosylated hemoglobin levels and is considered to be a useful, cost-effective treatment option for managing type
Mixtures: AMARYL®M 1 MG/ 500 MG, DUERID 30/2 MG TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesColesevelam
go.drugbank.com/drugs/DB00930ApprovedInvestigationalColesevelam is a bile acid sequestrant. … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood.
Products: ZENUM 625 MG FILM TABLET, 180 ADET, KOVEL 625 MG FİLM KAPLI TABLET, 180 ADETCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnIt is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. … Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Carbomer 974 (P), Carbomer homopolymer type BMarstacimab
go.drugbank.com/drugs/DB17725ApprovedInvestigationalMarstacimab is a human monoclonal immunoglobulin G Type 1 (IgG1) antibody produced by Chinese hamster ovary (CHO) cells by recombinant DNA technology. … [L51803] It is a tissue factor pathway inhibitor (TFPI) antagonist, which is an endogenous anticoagulant.
Synonyms: Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1-chain), disulfide with human monoclonal pf-06741086 .lambda.-chain, dimerCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsThiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalIt is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663] … Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_.
Synonyms: Thiocolchicine 2-glucoside analogMixtures: LEODEX PLUS 50 MG/8 MG FILM KAPLI TABLET,10 TABLET, TIYOKSEN 550 MG/8 MG FILM TABLET,10 ADETDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigational[A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological activity. … Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.
Synonyms: 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-olMixtures: CICLIDON 30 MG, Liberel 0,15 mg/0,03 mg FilmtablettenCabergoline
go.drugbank.com/drugs/DB00248ApprovedInvestigationalCabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome.
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AgonistsSynonyms: 1-((6-allylergolin-8β-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea, 1-[(6-allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylureaTeduglutide
go.drugbank.com/drugs/DB08900ApprovedInvestigationalTeduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. … Teduglutide differs from GLP-2 by one amino acid (alanine is substituted by glycine).
Synonyms: Gly(2)-GLP-2, (Gly2)GLP-2Categories: Glucagon-like Peptide-2 (GLP-2) Agonists, Alimentary Tract and MetabolismDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.
Synonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine, (S)-duloxetineCategories: Heterocyclic Compounds, 1-Ring, Serotonin and Noradrenaline Reuptake Inhibitors