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Displaying results 3081 - 3090 of 10000 in total
  1. Drug

    Lamivudine

    go.drugbank.com/drugs/DB00709
    ApprovedInvestigational

    It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.

    Mixtures: N/A, N/ACategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic Use
  2. Drug

    Vimseltinib

    go.drugbank.com/drugs/DB17520
    ApprovedInvestigational

    [L52230,A265035] Vimseltinib - under the brand name Romvimza - was approved by the FDA in February 2025 for the treatment of tenosynovial giant cell tumours for which surgical resection is not appropriate … [L52230] It is highly selective, with a >500-fold selectivity for CSF1R over its nearest off-target kinase.

  3. Drug

    Relatlimab

    go.drugbank.com/drugs/DB14851
    ApprovedInvestigational

    [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of unresectable or metastatic … [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well as the first to receive FDA approval.

  4. Drug

    mRNA-1010

    go.drugbank.com/drugs/DB22484
    Approved

    [L64058] The FDA approved mFLUSIVA on August 5, 2026 for active immunization against influenza in adults 50 years of age and older, making it the first mRNA-based influenza vaccine approved in the United … benefit to be confirmed in a postmarketing trial.

  5. Drug

    Penbutolol

    go.drugbank.com/drugs/DB01359
    ApprovedInvestigationalWithdrawn

    This binding characteristic of penbutolol is being investigated for its implications in Antidepressant Therapy. … Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker.

    Categories: Beta Blocking Agents, Non-Selective
  6. Drug

    Thrombin alfa

    go.drugbank.com/drugs/DB11572
    Approved

    The cell culture process used in the manufacture of Thrombin Alfa employs no additives of human or animal origin. … Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and is purified by a chromatographic

  7. Drug

    Nesiritide

    go.drugbank.com/drugs/DB04899
    ApprovedInvestigationalWithdrawn

    Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.

    Categories: Vasodilators Used in Cardiac Diseases
  8. Drug

    Phenacemide

    go.drugbank.com/drugs/DB01121
    Approved

    Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.

  9. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity.

    Categories: Antihypertensive Agents Indicated for HypertensionProducts: FELODIPIN 2.5MG RET HEU N
  10. Drug

    Daledalin

    go.drugbank.com/drugs/DB09189
    Experimental

    Daledin (UK-3557-15) is a selective norepinephrine reuptake inhibitor. It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties. … It was in trials for depression in the 1970s but never marketed.