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Displaying results 301 - 310 of 10000 in total
  1. Target

    Melanoma antigen preferentially expressed in tumors

    go.drugbank.com/bio_entities/BE0010493
    TargetHumans

    In the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin

    Polypeptides: Melanoma antigen preferentially expressed in tumors
  2. Target

    Protein-glutamine gamma-glutamyltransferase E

    go.drugbank.com/bio_entities/BE0001273
    TargetEnzymeHumans

    In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath … Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins.

    Polypeptides: Protein-glutamine gamma-glutamyltransferase ESynonyms: TG(E), TGase E
  3. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    In addition, they block many receptors other than the primary target (dopamine receptors), such as cholinergic or histaminergic receptors, resulting in a higher incidence of side effects such as sedation … [A180616] While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain,[A27477] it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
  4. Target

    Membrane protein involved in aromatic hydrocarbon degradation

    go.drugbank.com/bio_entities/BE0003979
    TargetPseudomonas putida (strain F1 / ATCC 700007)

    Polypeptides: Membrane protein involved in aromatic hydrocarbon degradation
  5. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation … [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids.

    Products: Vasopressin in 0.9% Sodium Chloride, Pitressin Inj 10 Unit/0.5ml
  6. Drug

    Iohexol

    go.drugbank.com/drugs/DB01362
    ApprovedInvestigational

    Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.

    Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideMixtures: Dexlido M-C, Mlk F4-C
  7. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … regulation in both children and adults.

    Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im Sc, Nutropin - Kit Pws(10mg) & Liq(10ml) Im ScCategories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inducers
  8. Drug

    Coagulation Factor IX Human

    go.drugbank.com/drugs/DB13152
    ApprovedInvestigational

    Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.

    Synonyms: Antihemophilic factor B, Factor IX (Human)Mixtures: Beriplex P/n 500, Beriplex P/n 1000
  9. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    It can be used in severe cases of croup [L4824]. … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions.

    Synonyms: 1,2-BENZENEDIOL, 4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-, (R)-, 4-((1R)-1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-BENZENEDIOLInternational brands: Epi EZ Pen JR
  10. Drug

    Gadodiamide

    go.drugbank.com/drugs/DB00225
    ApprovedInvestigational

    Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels. … [A263096] Approved by the FDA in 1993, gadodiamide is the first non-ionic GBCA to be used.

    Categories: Compounds used in a research, industrial, or household settingProducts: OMNISCAN® INYECTABLE, OMNISCAN INJECTION 0.5MMOL/ML-10ML IN GLASS VIAL