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Displaying results 301 - 310 of 688 in total
  1. Pathway

    Lonoctocog Alfa Action Pathway

    smpdb.ca/view/SMP0126848
    Drug action

    Lonoctocog alfa also known as Afstyla is a recombinant coagulation factor VIII that is used in the treatment of hemophilia A.

    Drugs: Calcium · Lonoctocog alfa
  2. Pathway

    Moroctocog Alfa Action Pathway

    smpdb.ca/view/SMP0126849
    Drug action

    Moroctocog alfa is administered intravenously used to treat hemophilia A to control bleeding. … Moroctocog alfa also known as Refacto AF and Xyntha, is a B-domain deleted recombinant factor VIII similar to the endogenous coagulation factor VIII.

    Drugs: Calcium · Moroctocog alfa
  3. Pathway

    Turoctocog Alfa Action Pathway

    smpdb.ca/view/SMP0126775
    Drug action

    It is administered intravenously and acts similarly to coagulation factor VIII, forming a complex with IX in order to activate factor X leading to a blood clot forming. … Turoctocog alfa allows the missing factor coagulation VIII to be replaced and restore blood clotting.

    Drugs: Calcium · Turoctocog alfa
  4. Drug

    Adegramotide

    go.drugbank.com/drugs/DB17248
    Investigational

    Synonyms: Trp-ala-pro-val-leu-asp-phe-ala-pro-pro-gly-ala-ser-ala-tyr-gly-ser-leu
  5. Target

    serine-type D-Ala-D-Ala carboxypeptidase

    go.drugbank.com/bio_entities/BE0004643
    TargetStreptococcus pneumoniae

    Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

    Polypeptides: serine-type D-Ala-D-Ala carboxypeptidaseFunction: serine-type D-Ala-D-Ala carboxypeptidase activity
  6. Indication

    Refractory Complex partial seizures

    go.drugbank.com/conditions/DBCOND0022730
    Drugs: Vigabatrin
    Synonyms: Complex partial status epilepticus, Refractory Complex partial seizures
  7. Drug

    Pralmorelin

    go.drugbank.com/drugs/DB18252
    Experimental

    Synonyms: D-ala-3-(2-naphthyl)-d-ala-ala-trp-d-phe-lys-nh2
  8. Drug

    Denileukin diftitox

    go.drugbank.com/drugs/DB00004
    ApprovedInvestigational

    recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub>387</sub>)-His and the sequence for human interleukin-2 (IL-2; Ala

    Synonyms: N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2
  9. Pathway

    Turoctocog Alfa Pegol Action Pathway

    smpdb.ca/view/SMP0126856
    Drug action

    The difference between turoctocog alfa pegol and turoctocog alfa is the modification to the structure of turoctocog alfa pegol extends its half-life. … Turoctocog alfa pegol is a version of turoctocog alfa also known as esperoct, used to treat hemophilia A.

    Drugs: Calcium · Turoctocog alfa pegol
  10. Pathway

    Peginterferon alfa-2a Action Pathway

    smpdb.ca/view/SMP0125981
    Drug action

    This receptor complex also phosphorylates STAT3 homodimers. The IFNAR complex phorphoylates STAT5 which binds with Crk-like protein (CRKL). … Peginterferon alfa-2a is a modified form of recombinant human interferon, which is used to activate interferon alpha receptors in the JAK-STAT pathway.

    Drugs: Peginterferon alfa-2a