serine-type D-Ala-D-Ala carboxypeptidase

BE0004643ProteinStreptococcus pneumoniaepbp3

Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. It is acted on by 19 drugs in DrugBank.

Gene name
pbp3
UniProtKB entry
Q75Y35TrEMBL
Residues / weight
413 residues · 45,210 Da
Also known as
3.4.16.4 · Penicillin-binding protein 3 · Putative D-alanyl-D-alanine carboxypeptidase

Resolves to

Protein
UniProtQ75Y35UniProt nameQ75Y35_STREE
Drugs

What you can answer from here — as of May 03, 2025

19DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on serine-type D-Ala-D-Ala carboxypeptidase, how selective are they, and which programs against it are still in active trials?

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