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Displaying results 301 - 310 of 10000 in total
  1. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    [A181397, A181403] Atorvastatin was first synthesized in 1985 by Dr. Bruce Roth and approved by the FDA in 1996. … [T568] It is a pentasubstituted pyrrole [A177415] formed by two contrasting moieties with an achiral heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound.

    Mixtures: ATOZET TABLET 10MG/20MG, CADUET TABLETS 10MG/20MGCategories: atorvastatin and ezetimibe, atorvastatin and amlodipine
  2. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, clomipramine exerts a positive effect on mood. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineCategories: Tricyclics and Other Norepinephrine-reuptake Inhibitors, Non-Selective Monoamine Reuptake Inhibitors
  3. Drug

    Benazepril

    go.drugbank.com/drugs/DB00542
    ApprovedInvestigational

    Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].

    Mixtures: CIBADREX 20MG/25MG, CIBADREX 20MG/25MGCategories: ACE Inhibitors and Diuretics, benazepril and diuretics
  4. Drug

    Prazosin

    go.drugbank.com/drugs/DB00457
    ApprovedInvestigational

    Prazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. … Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares.[A176618, A176621, A176624]

    Categories: prazosin and diuretics, Alpha-Adrenoreceptor Antagonists and DiureticsProducts: Nu-prazo Tab 1mg, Nu-prazo Tab 2mg
  5. Drug

    Fluconazole

    go.drugbank.com/drugs/DB00196
    ApprovedInvestigational

    It was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues.

    Mixtures: FLUCONAZOL+SECNIDAZOL 75MG/1000 MG, FLUCONAZOL+SECNIDAZOL 75MG/1000 MGCategories: Imidazole and Triazole Derivatives, Triazole and tetrazole derivatives
  6. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Synonyms: 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: LOSARPLUS AL 100MG/25MG, LOSARPLUS AL 100MG/25MG
  7. Drug

    Synthetic camphor

    go.drugbank.com/drugs/DB14156
    Approved

    Mixtures: No Touch Chest Rub Rite Aid, Sore No MoreProducts: CBD Clinic - Mild To Moderate Muscle and Joint Pain Relief, Sore No More Warm Therapry Plus CBD 2000mg
  8. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.

    Mixtures: IMPLICOR 25MG/5MG FILM-COATED TABLETS, IMPLICOR 50MG/5MG FILM-COATED TABLETSCategories: metoprolol and thiazides, metoprolol and felodipine
  9. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    [A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014. … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.

    Categories: nivolumab and relatlimab, Amino Acids, Peptides, and ProteinsProducts: OPDIVO®100MG/10ML, Opdivo 10mg/ml, Concentrate for solution for infusion
  10. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.

    Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Antipruritics and Local Anesthetics, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use