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Polatuzumab vedotin
go.drugbank.com/drugs/DB12240ApprovedInvestigationalPolatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal...
Erdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine acts to control mucus production and control its viscosity while increasing mucociliary transport. It also combats the effects of free radicals resulting from cigarette smoke. … with acute infective exacerbation of chronic bronchitis resulted in higher concentrations of the antibiotic in the sputum, leading to earlier and more pronounced amelioration of clinical symptoms compared
Ezetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[L11347] Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick
Mixtures: ZETEZE-SM TABLETS 10+80MG, ZETEZE-SM TABLETS 10+40 MGXEN-2174
go.drugbank.com/drugs/DB05012ExperimentalXEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the Norepinephrine Transporter (NET).
Oxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to seve...
Mixtures: OXYCODON COMP 1A 10/5MG, OXYCODON COMP 1A 10/5MGCategories: Semi-synthetic OpioidsMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label] . It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and highe...
Squalene
go.drugbank.com/drugs/DB11460ApprovedInvestigationalVet approvedWithdrawnIt is ubiquitously distributed in human tissues where it is transported in serum generally in association with very low density lipoproteins. Squalene is investigated as an adjunctive cancer therapy.
Testosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalAs recent as 1 October 2018, the US FDA approved Antares Pharma Inc.'
A-16L
go.drugbank.com/drugs/DB18270ExperimentalSynonyms: ALA-GLN-TYR-ILE-LYS-ALA-ASN-SER-LYS-PHE-ILE-GLY-ILE-THR-GLU-LEUAtovaquone
go.drugbank.com/drugs/DB01117ApprovedInvestigationalAtovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.