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Daptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … [A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing
Categories: P-glycoprotein substratesProducts: DAPTOMICINA DR. REDDY'STriclocarban
go.drugbank.com/drugs/DB11155ApprovedIn 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal … Triclocarban, with the chemical formula C13H9Cl3N2O [L2675] is an antibacterial agent that is particularly effective against Gram-positive bacteria such as *Staphylococcus aureus*.
Products: DG Body Antibacterial Deodorant 3.5 oz barCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … D<sub>3</sub>.
Synonyms: 1α,25-dihydroxyvitamin D3, 1-alpha-25-Dihydroxyvitamin D3Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesIsoconazole
go.drugbank.com/drugs/DB08943ApprovedIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Products: NITRATO DE ISOCONAZOL CREMA1%Histamine
go.drugbank.com/drugs/DB05381ApprovedInvestigationalA depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Mixtures: DR. MIKES Ponos Pain Relief Cream Roll-OnCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Enzyme InhibitorsPhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalPhenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis. … Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores.
Mixtures: Au Kah Chuen Skin Lotion, Kank-A with Blistex Medicated LipProducts: Dg Health Sore ThroatIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nu-indapamide, COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADATretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.
Mixtures: AE BAN CREMA, Dr. Throwers HydrotetCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigationalSulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resis...
Mixtures: SULAMP® DUO TABLETA RECUBIERTAProducts: PENTICLOX-DUOSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed pur...
Mixtures: SPIRO D TABLINEN 100MGCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors