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Tralokinumab
go.drugbank.com/drugs/DB12169ApprovedInvestigationalWhile AD is a heterogenous condition with a variety of apparent genetic and environmental causes,[A242422] it is primarily driven by the pro-inflammatory cytokine interleukin-13 (IL-13). … [A242427] Tralokinumab is a fully human IgG4 monoclonal antibody targeted against IL-13.
Bifenthrin
go.drugbank.com/drugs/DB15056ExperimentalBifenthrin is under investigation in clinical trial NCT01560247 (Percutaneous Recanalization in Ischemic Stroke Management in Europe Observational Registry).
Erythema Nodosum Leprosum
go.drugbank.com/conditions/DBCOND0036567Drugs: ThalidomideSynonyms: Immune complex reaction co-occurrent and due to multibacillary leprosy, Immune complex reaction co-occurrent and due to multibacillary leprosy (disorder)Etozoline
go.drugbank.com/drugs/DB08982ExperimentalEtozoline is marketed in Europe under the names Diulozin, Elkapin, and Etopinil. Etozoline is a loop diuretic.
Categories: Heterocyclic Compounds, 1-RingNicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnNicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. … It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels.
Categories: Heterocyclic Compounds, 1-RingSynonyms: N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate (ester)Estriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedIt has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes. … A hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen.
Mixtures: GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETCategories: P-glycoprotein inducers, P-glycoprotein substratesMetamizole
go.drugbank.com/drugs/DB04817ApprovedInvestigationalWithdrawn[A251805] Metamizole is still used in certain countries in Europe, Asia and South America.[A251805] … Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability.
Mixtures: ANTIALGINA®, CAFETRIN ®Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A InducersDiethylamino hydroxybenzoyl hexyl benzoate
go.drugbank.com/drugs/DB11269ApprovedDiethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the U.S., South America, Mexico, Japan and Taiwan. … Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range.
Mixtures: D-one By Tamdoan Bb Light, D-one By Tamdoan Bb MediumSynonyms: Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoateMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigational[L39327] The drug was also approved by Health Canada in September 2022 [L43262] and by European Commission in November 2022.[L44411]
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet)Ambrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalIt is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. … Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid