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Oxaliplatin
go.drugbank.com/drugs/DB00526ApprovedInvestigational[A796,A797] This is an effective combination treatment both as a first-line treatment and in patients refractory to an initial fluorouracil and leucovorin combination. … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.
Categories: OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: L-OHP, (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUMProtamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalSince it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps … Regardless, protamine sulfate continues to see contemporary use given its genuine effectiveness in reversing heparin effects.
Products: Protamine Sulfate Inj 10mg/ml USP, PROLFAT 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADETSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigational[L50131] When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.[A263296] … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.
Mixtures: AUROPENNZ 1.5 G POLVO ESTERIL PARA RECONSTITUIR A SOLUCION INYECTABLE, SULPERAZON 1G IM/IVProducts: B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 5 ADET, B-LAKTAM 1 GR IM/IV ENJEKTABL TOZ ICEREN FLAKON, 100 ADETMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThe pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue … [A221048, A221053, A221058, A221063, A221068, L16518] Mepolizumab is a fully-humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/MLBenralizumab
go.drugbank.com/drugs/DB12023ApprovedInvestigationalIt is an afucosylated IgG which gives it high affinity for the FcγRIIIα receptor in natural killer cells, macrophages and neutrophils. … Benralizumab is a humanized recombinant monoclonal antibody of the isotype IgG1k immunoglobulin that specifically binds to the alpha chain of the interleukin 5 receptor (IL-5R) expressed on eosinophils
Products: Fasenra 30 mg solution for injection in pre-filled syringe, Fasenra 30mg Solution for Injection in Pre-filled PenInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalInterferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Intron ACategories: Interferon Type IPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977. … [A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]
Products: MENEDRON-L 15 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON (4 FLAKON), MENEDRON-L 30 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON (3 FLAKON)Gallium citrate Ga-67
go.drugbank.com/drugs/DB06784ApprovedAlthough the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation … Gallium citrate Ga 67 is the citrate salt of the radioisotope gallium Ga 67.
Synonyms: Gallium (67 Ga) citrate, Gallium citrate Ga 67Products: GA - 67 MM-1, Gallium Citrate Ga-67Ensulizole
go.drugbank.com/drugs/DB11115ApprovedIt is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. … Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less oily [A32259].
Mixtures: Too Cool For School DINOPLATZ La Ola Noche No.23, Too Cool For School DINOPLATZ La Ola Viento No.21Products: Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation, Covergirl Trublend Base Business Skin Primer Base Pour LA PeauProtein C
go.drugbank.com/drugs/DB11312ApprovedInvestigationalProtein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. … APC exerts its effect by inactivating essential components of the coagulation cascade (specifically factors V and VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot
Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETProducts: CEPROTIN 500 IU IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON