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Displaying results 3101 - 3110 of 10000 in total
  1. Drug

    Vutrisiran

    go.drugbank.com/drugs/DB16699
    ApprovedInvestigational

    [A249010] More than 130 TTR mutations have been identified so far,[A249015] but the most common one is the replacement of valine with methionine at position 30 (Val30Met). … [A249010] TTR mutations lead to the formation of misfolded TTR proteins, which form amyloid fibrils that deposit in different types of tissues.

  2. Drug

    Tafenoquine

    go.drugbank.com/drugs/DB06608
    ApprovedInvestigational

    [A35677] It was FDA approved on July 20, 2018.[L3770] … Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  3. Indication

    Tick-Borne Encephalitis, European

    go.drugbank.com/conditions/DBCOND0144103
    Drugs: Tick-borne encephalitis vaccine (whole virus, inactivated)
    Synonyms: Encephalitis due to tick-borne encephalitis virus (navigational concept)
  4. Drug

    Atoltivimab

    go.drugbank.com/drugs/DB15898
    ApprovedInvestigational

    [A221825] Immune therapy using monoclonal antibodies (mAbs) is becoming an increasingly attractive therapeutic method to combat infectious diseases due to its rapid development, low toxicity, and high … INMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320]

  5. Drug

    Fosnetupitant

    go.drugbank.com/drugs/DB14019
    ApprovedInvestigational

    Generally, 25% to 30% of patients with a diagnosis of cancer receive chemotherapy as a treatment modality and 70% to 80% of these patients undergoing chemotherapy treatment may experience nausea and vomiting

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  6. Drug

    Potassium carbonate

    go.drugbank.com/drugs/DB13977
    Approved

    It presents a large capacity to absorb moisture.

    Mixtures: Buffered Vitamin C Powder With Ca Mg and K, Vit C W Calc-mag and Potass Powder
  7. Target

    Mucin-16

    go.drugbank.com/bio_entities/BE0002439
    TargetHumans

    Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces

    Polypeptides: Mucin-16Synonyms: MUC-16
  8. Target

    Claudin-16

    go.drugbank.com/bio_entities/BE0009861
    TransporterHumans

    In the thick ascending limb (TAL) of Henle's loop, facilitates sodium paracellular permeability from the interstitial compartment to the lumen, contributing to the lumen-positive transepithelial potential

    Polypeptides: Claudin-16
  9. Indication

    Catheter-related Bloodstream Infection

    go.drugbank.com/conditions/DBCOND0037994
    Drugs: Cefazolin · Doripenem · Taurolidine
    Synonyms: Bloodstream infection due to central venous catheter
  10. Drug

    Thyme

    go.drugbank.com/drugs/DB10983
    Approved

    Thyme allergenic extract is used in allergenic testing.

    Mixtures: MENTOSEPTOL GARGARA, 100 ML, BRONCHİPRET ŞURUP, 50 ML