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Bromodiphenhydramine
go.drugbank.com/drugs/DB01237ApprovedBromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. … Ethanolamine antihistamines produce marked sedation in most patients.
Synonyms: 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamineSulfadimethoxine
go.drugbank.com/drugs/DB06150ApprovedVet approvedWithdrawnIt is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. … It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.
Synonyms: N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamideAmoxapine
go.drugbank.com/drugs/DB00543ApprovedThey contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.
IDM-2
go.drugbank.com/drugs/DB05293ExperimentalIDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.
Plerixafor
go.drugbank.com/drugs/DB06809ApprovedInvestigational[A7117,L45678] It is used to stimulate the release of stem cells from the bone marrow into the blood in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma to stimulate their immune system. … Since CXCR4 and SDF-1α are involved in the trafficking and homing of CD34+ cells to the marrow compartment, blocking this interaction leads to an increase in CD34+ cell circulating levels.
Products: AUROPLERISTEM 20 MG/ML, Mozobil 20 mg/ml solution for injectionSuvorexant
go.drugbank.com/drugs/DB09034ApprovedInvestigationalIt has been approved for the treatment of insomnia.
Products: BELSOMRA® 15 MG, BELSOMRA® 10 MGCosibelimab
go.drugbank.com/drugs/DB15770ApprovedInvestigationalOn December 13, 2024, cosibelimab was approved by the FDA for the treatment of metastatic or locally advanced cutaneous squamous cell carcinoma [L52690] as the first approved anti-PD-L1 therapy in the
Pipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnHowever, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.
Products: TRIPIPOT® SOLUCIÓN INYECTABLE 25 MG/ML, PIPOTAZ®25 MG/ ML SOLUCION INYECTABLEAmlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. … Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population.