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Anacaulase
go.drugbank.com/drugs/DB17449ApprovedInvestigationalcomposed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsOTL-201
go.drugbank.com/drugs/DB17652ExperimentalIt consists of a lentiviral vector to insert a functional copy of the human N-Sulfoglucosamine Sulfohydrolase (SGSH) gene into autologous CD34+ hematopoietic stem cells.[L45973]
Tralesinidase alfa
go.drugbank.com/drugs/DB17657InvestigationalTralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known ...
Synonyms: Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein, Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2Categories: beta-N-AcetylhexosaminidasesNix-0699
go.drugbank.com/drugs/DB17732ExperimentalCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsDaxibotulinumtoxinA
go.drugbank.com/drugs/DB17929ApprovedInvestigationalDaxibotulinumtoxinA is an acetylcholine release inhibitor and neuromuscular blocking agent. It is a botulinum toxin without accessory proteins purified from the bacterium Clostridium botulinum type A, the gram-positive anaerobic bacteriu...
Acoramidis
go.drugbank.com/drugs/DB17999ApprovedInvestigationalAcoramidis is a small molecule stabilizer of transthyretin (TTR) for use in patients with TTR amyloidosis. Similar to the previously developed tafamidis, acoramidis is used to stabilize TTR in its tetrameric form, preventing the formatio...
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsQuinoline
go.drugbank.com/drugs/DB18050InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesOpelconazole
go.drugbank.com/drugs/DB18251InvestigationalCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersrAAV9-hNAGLU
go.drugbank.com/drugs/DB18415ExperimentalrAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase.