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Generalized tonic-clonic Seizures
go.drugbank.com/conditions/DBCOND0050096Synonyms: Other generalized epilepsy and epileptic syndromesDiclofenamide
go.drugbank.com/drugs/DB01144ApprovedA carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Categories: Antiglaucoma Preparations and Miotics, Genito Urinary System and Sex HormonesHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansExpressed on T-cells, promotes conjugation but not engulfment of apoptotic cells. … Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance (PubMed:14556005).
Synonyms: T-cell immunoglobulin and mucin domain-containing protein 3Modified vaccinia ankara
go.drugbank.com/drugs/DB15483ApprovedInvestigationalVaccines using MVA are live and non-replicating, and are produced using Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN).[L42660,L42670] … Modified Vaccinia Ankara (MVA) refers to an attenuated strain of the Vaccinia virus.
Potassium perchlorate
go.drugbank.com/drugs/DB09418ApprovedWithdrawnPotassium perchlorate acts as a competitive inhibitor of iodine uptake by the thyroid gland and attenuates the production of the thyroid hormone. … Potassium is most commonly used in flares and automobile airbags [A32609].
Categories: Sex Hormones and InsulinsIdecabtagene vicleucel
go.drugbank.com/drugs/DB16665ApprovedInvestigational[A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from a patient to express a CAR for a tumor specific antigen. … [L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA on August 18, 2021.[L51003]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic cell and gene therapyRelugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigational[A225926] In May 2021, the FDA approved the combination product made up of relugolix, [estradiol], and [norethindrone] under the market name Myfembree for the first once-daily treatment for the management … administration - and therefore provides a less burdensome therapeutic option for patients who might otherwise require clinic visits for administration by healthcare professionals.
Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsDesflurane
go.drugbank.com/drugs/DB01189ApprovedInvestigationalDesflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as [methoxyflurane], [sevoflurane], [enflurane], or [isoflurane]. … It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]
Dexfenfluramine
go.drugbank.com/drugs/DB01191ApprovedIllicitWithdrawnFor a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss.
Categories: Alimentary Tract and MetabolismDotatate gallium Ga-68
go.drugbank.com/drugs/DB13925ApprovedInvestigationalWithdrawnGa-68 dotatate has a high affinity for somatostatin-2 receptor and it is rapidly excreted from the nontarget sites which gives it an ideal candidate for imaging neuroendocrine tumors. … [A31358] Dotatate gallium 68 was developed by Advanced Accelerator Applications USA, Inc. and FDA approved in June 1, 2016.
Categories: Amino Acids, Peptides, and Proteins