Modified vaccinia ankara

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Modified vaccinia ankara
DrugBank Accession Number
DB15483
Background

Not Available

Type
Biotech
Groups
Approved
Biologic Classification
Vaccines
Attenuated
Synonyms
  • Modified Vaccinia Virus (Ankara-Bavarian Nordic)
  • MVA
  • MVA-BN
  • Vaccinia strain modified ankara

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbataceptThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Abatacept.
AdalimumabThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Adalimumab.
AldesleukinThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Aldesleukin.
AlefaceptThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Alefacept.
AlemtuzumabThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Alemtuzumab.
AltretamineThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Altretamine.
AmsacrineThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Amsacrine.
AnakinraThe therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Anakinra.
Antilymphocyte immunoglobulin (horse)The therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Antilymphocyte immunoglobulin (horse).
Antithymocyte immunoglobulin (rabbit)The therapeutic efficacy of Modified vaccinia ankara can be decreased when used in combination with Antithymocyte immunoglobulin (rabbit).
Interactions
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Food Interactions
Not Available

Products

Products2
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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
ImvamuneSuspension50000000 CCID50 / 0.5 mLSubcutaneousBavarian Nordic As2015-06-15Not applicableCanada flag
ImvanexInjection, suspension50000000 Inf. USubcutaneousBavarian Nordic A/S2020-12-18Not applicableEU flag
MvabeaInjection, suspension70000000 Inf. UIntramuscularJanssen Cilag International Nv2021-02-11Not applicableEU flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
JDS6958QAG
CAS number
Not Available

References

General References
Not Available
RxNav
1668221

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionVaccinations1
3Active Not RecruitingPreventionEbola1
3Active Not RecruitingPreventionEbolavirus Disease1
3Active Not RecruitingPreventionHemorrhagic Fever, Ebola1
3Active Not RecruitingPreventionMonkeypox Virus Infection1
3CompletedPrevention18-42 Year Old Healthy Vaccinia-naïve Subjects1
3CompletedPreventionHealthy Subjects (HS)2
3CompletedPreventionVariola Major (Smallpox)2
2Active Not RecruitingSupportive CareAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Acute Lymphoblastic Leukemia in Remission / Acute myeloid leukaemia (in remission) / Agnogenic Myeloid Metaplasia / Chronic Lymphocytic Leukemia (CLL) / Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive / Cytomegaloviral Infection / Lymphadenopathy / Lymphoma, Hodgkins / Lymphoma, Lymphoblastic / Myelodysplastic Syndromes (MDS) / Myeloproliferative Neoplasms (MPNs) / Non-Hodgkin's Lymphoma (NHL)1
2Active Not RecruitingTreatmentInfections, Respiratory Syncytial Virus1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SuspensionSubcutaneous50000000 CCID50 / 0.5 mL
Injection, suspensionSubcutaneous50000000 U.inf.
Injection, suspensionSubcutaneous50000000 Inf. U
Injection, suspensionIntramuscular0.5 ML
Injection, suspensionIntramuscular70000000 Inf. U
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on August 30, 2019 17:59 / Updated on October 24, 2021 16:00