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Fluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalIt was launched in the US in December 1994 and in Japan in June 1999. As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients.
Categories: Metabolic Side Effects of Drugs and Substances, P-glycoprotein inhibitorsProducts: FAVERIN 50 MG, VERLIN TABLETAS X 50 MGAcarbose
go.drugbank.com/drugs/DB00284ApprovedInvestigationalAcarbose is therefore used in conjunction with diet, exercise, and other pharmacotherapies for the management of blood sugar levels in patients with type 2 diabetes. … Acarbose is a complex oligosaccharide that acts as an inhibitor of several enzymes responsible for the breakdown of complex carbohydrates in the intestines.
Categories: metformin and acarbose, Alimentary Tract and MetabolismProducts: GLUCOBAY 50 TABLET 50 mg, ACARBOSA 50 MGYohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Synonyms: (16α,17α)-17-hydroxyyohimban-16-carboxylic acid methyl esterInternational brands: Baron-XVindesine
go.drugbank.com/drugs/DB00309ApprovedInvestigationalWithdrawnMajor side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (antineoplastic combined chemotherapy protocols).
Synonyms: 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastineCategories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexEthambutol
go.drugbank.com/drugs/DB00330ApprovedInvestigationalEthambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis. … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.[A229048] Ethambutol was granted FDA approval on 6 November 1967.
Mixtures: RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: MATE 1 Substrates, ethambutol and isoniazidAcute Hepatitis C Genotype 5
go.drugbank.com/conditions/DBCOND0173314Synonyms: Genotype 5 Acute Hepatitis C, Acute Hepatitis C Genotype 5Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Phytochlorin
go.drugbank.com/drugs/DB19265InvestigationalPhytochlorin is under investigation in clinical trial NCT06311890 (Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(pdt) With Chlorin-e6 in Treating Moderate to Severe Acne
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsSynonyms: 21h,23h-porphine-7-propanoic acid, 3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-, (7s,8s)-, 2-porphinepropionic acid, 18-carboxy-20-(carboxymethyl)-13-ethyl-2.beta.,3-dihydro-3.beta.,7,12,17-tetramethyl-8-vinyl-Darunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.
Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, FURTHAS®R TABLETAS RECUBIERTASCategories: Heterocyclic Compounds, 1-Ring, Experimental Unapproved Treatments for COVID-19Benzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalIt is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. … potency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: benzhydryl 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ether, 3α-benzhydryloxy-8-methyl-8-azabicyclo[3.2.1]octane