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Etidocaine
go.drugbank.com/drugs/DB08987ApprovedIt is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Alfimeprase
go.drugbank.com/drugs/DB04919InvestigationalIt is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo. … Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (<i>Agkistrodon contortrix contortrix</i>).
Carthamus tinctorius flower bud
go.drugbank.com/drugs/DB14278ApprovedCarthamus tinctorius flower bud is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Zanthoxylum clava-herculis whole
go.drugbank.com/drugs/DB14353ApprovedZanthoxylum clava-herculis whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
rhThrombin
go.drugbank.com/drugs/DB04923ApprovedWithdrawnZymoGenetics is developing rhThrombin, a recombinant form of human thrombin that is not derived from animal or human blood, as an aid to controlling bleeding during surgery. … The production of recombinant proteins is not dependent on the availability of blood from animals or human donors and can be scaled-up to meet market demand.
Piperaquine
go.drugbank.com/drugs/DB13941ApprovedInvestigationalPiperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550]. … Its use declined in the 1980's as piperaquine resistant strains of *Plasmodium falciparum* appeared and artemisinin derivatives became available.
Tesmilifene
go.drugbank.com/drugs/DB04905InvestigationalTesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast
Buformin
go.drugbank.com/drugs/DB04830ApprovedWithdrawnBuformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. … It was withdrawn from the market in most countries due to a high risk of causing lactic acidosis.
Ascorbyl phosphate
go.drugbank.com/drugs/DB11352ApprovedInvestigationalAs vitamin C is susceptible to breakdown of compound and discoloration in cosmetic formulations, ascorbyl phosphate, along with other Vitamin C derivatives, acts as an active and stable precursor of vitamin … While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate an antioxidant action to act as a free radical scavenger and increases collagen production *in vitro