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Displaying results 3141 - 3150 of 9886 in total
  1. Drug

    Podofilox

    go.drugbank.com/drugs/DB01179
    Approved

    A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. … It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives

  2. Drug

    Linaprazan

    go.drugbank.com/drugs/DB20602
    Investigational

    Linaprazan has a monoisotopic molecular weight of 366.21 Da. … Linaprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Linaprazan is a proton pump inhibitor, not dependent on acid activation.

  3. Drug

    Prusogliptin

    go.drugbank.com/drugs/DB20606
    Investigational

    Prusogliptin has a monoisotopic molecular weight of 324.2 Da. … Prusogliptin is a small molecule drug. The usage of the INN stem '-gliptin' in the name indicates that Prusogliptin is a dipeptidyl aminopeptidase-IV inhibitor.

  4. Drug

    Amsilarotene

    go.drugbank.com/drugs/DB21085
    Investigational

    Amsilarotene has a monoisotopic molecular weight of 385.15 Da. … Amsilarotene is a small molecule drug. The usage of the INN stem '-arotene' in the name indicates that Amsilarotene is a arotinoid derivative.

  5. Drug

    Guretolimod

    go.drugbank.com/drugs/DB21487
    Investigational

    Guretolimod has a monoisotopic molecular weight of 513.26 Da. … Guretolimod is a small molecule drug. The usage of the INN stem '-tolimod' in the name indicates that Guretolimod is a toll-like receptor (TLR) agonist.

  6. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    Ocedurenone has a monoisotopic molecular weight of 503.21 Da. … Ocedurenone is a small molecule drug. The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  7. Drug

    Selnoflast

    go.drugbank.com/drugs/DB21522
    Investigational

    Selnoflast has a monoisotopic molecular weight of 391.19 Da. … Selnoflast is a small molecule drug. The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor.

  8. Drug

    Brimarafenib

    go.drugbank.com/drugs/DB21706
    Investigational

    Brimarafenib has a monoisotopic molecular weight of 482.12 Da. … Brimarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.

  9. Drug

    Melatonin

    go.drugbank.com/drugs/DB01065
    ApprovedInvestigationalNutraceuticalVet approved

    The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus … Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Ligelizumab

    go.drugbank.com/drugs/DB11856
    Investigational

    Similar in mechanism to [omalizumab], another IgE-directed monoclonal antibody, ligelizumab has a distinct binding epitope as compared to its peer (with a small degree of overlap) which appears to confer … Ligelizumab is a humanized IgG1k monoclonal antibody targeted against immunoglobulin E (IgE).