Search
Penicillium italicum
go.drugbank.com/drugs/DB10811ApprovedPenicillium italicum is a fungus which can provoke allergic reactions. Penicillium italicum extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixturePericiazine
go.drugbank.com/drugs/DB01608ApprovedPericiazine is a phenothiazine of the piperidine group. … Pericyazine, like other phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a central adrenergic blockade.
Synonyms: 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine, Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazineCategories: Heterocyclic Compounds, 3-Ring, Adrenergic alpha-1 Receptor AntagonistsSutilain
go.drugbank.com/drugs/DB09379ApprovedWithdrawnSutilain is a member of the keratase family which includes agents such as papain. It is able to dissolve the intercellular matrix which helps with desquamation. … Sutilain contains proteolytic enzymes derived from _Bacillus subtilis_ and it is available as a cream-colored odorless powder.
Pembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigational[F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma by the FDA on September 4, 2014,[L2954] becoming the first approved therapy against PD-1. … [A7624] In the time since its initial approval, pembrolizumab has been granted approval in the treatment of a wide variety of cancers.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: Keytruda Sc, KEYTRUDA SCBoceprevir
go.drugbank.com/drugs/DB08873ApprovedWithdrawnHCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … Boceprevir is available as a fixed dose product (tradename Victrelis) used for the treatment of chronic Hepatitis C.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: VICTRELIS ® CAPSULAS 200 MG (MOLECULA PROTEGIDA)Somapacitan
go.drugbank.com/drugs/DB15093ApprovedInvestigationalSomapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency. … [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), SOGROYA® 5MG/1.5MLIsopropyl myristate
go.drugbank.com/drugs/DB13966Approved[A178078] At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse [A32333, L1964, L1966]. … Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Synonyms: 1-Methylethyl tetradecanoateBulevirtide
go.drugbank.com/drugs/DB15248ApprovedInvestigationalHepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality. … It was first approved for use in the EU on May 28, 2020; bulevirtide has been granted PRIME scheme eligibility and Orphan Drug Designation by the European Medicines Agency.
International brands: Myrcludex BZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. … In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateBronopol
go.drugbank.com/drugs/DB13960ApprovedThe agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic … Compared to other aliphatic halogen-nitro compounds, bronopol is more stable to hydrolysis in aqueous media under normal conditions [A32792].
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Bromo-2-nitropropane-1,3-diol, 2-Nitro-2-bromo-1,3-propanediol