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Displaying results 3151 - 3160 of 10000 in total
  1. Drug

    Olokizumab

    go.drugbank.com/drugs/DB13127
    Investigational

    Interleukin-6 (IL-6) is an important cytokine with roles in immune cell proliferation/differentiation, energy and bone metabolism, and the acute phase response of the innate immune system. … IL-6 pathway dysregulation is associated with chronic inflammation and lymphoproliferation, including in autoimmune conditions such as rheumatoid arthritis, Castleman disease, and cytokine release syndrome

  2. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration. … As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.

  3. Drug

    Thioglycolic acid

    go.drugbank.com/drugs/DB15429
    Investigational

    Thioglycolic acid is under investigation in clinical trial NCT03238105 (Treatment of Periorbicular Hyperchromia Comparing 10% Thioglycolic Acid Peeling Versus Pulsed Intense Light).

  4. Drug

    Mespirenone

    go.drugbank.com/drugs/DB20625
    Experimental

    The usage of the INN stem '-renone' in the name indicates that Mespirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  5. Drug

    Stannous fluoride

    go.drugbank.com/drugs/DB11092
    ApprovedInvestigational

    It is an FDA-approved over-the-counter product. … Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity.

    Categories: Compounds used in a research, industrial, or household settingProducts: H E B Restore and Defend, Pro-Den Rx
  6. Drug

    Bromchlorenone

    go.drugbank.com/drugs/DB20459
    Experimental

    The usage of the INN stem '-renone' in the name indicates that Bromchlorenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  7. Drug

    Pegulicianine

    go.drugbank.com/drugs/DB18731
    ApprovedInvestigational

    Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. … [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a fluorescent signal that can be detected using a fluorescence imaging device.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    It is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.

    Mixtures: Racord Two No 8, Sil Trax Plus No 8Products: Orostat 8%, Sil Trax Epi No 8
  9. Drug

    Rutin

    go.drugbank.com/drugs/DB01698
    ApprovedInvestigational

    A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.

    Mixtures: Nutriforte Non-Acidic Vitamin C 1000 mg with Bioflavonoids
  10. Drug

    Inulin

    go.drugbank.com/drugs/DB00638
    ApprovedInvestigationalNutraceutical

    It has been used in physiologic investigation for determination of the rate of glomerular function. … A starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.

    Mixtures: GLP CoreCategories: Compounds used in a research, industrial, or household setting