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Fidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigationalfrom week 12 to month 15 compared to an ABR of 4.43 for the pre-treatment period. … Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B.
Pemigatinib
go.drugbank.com/drugs/DB15102ApprovedInvestigationalPemigatinib is a small molecule kinase inhibitor with antitumour activity. … [A193719] FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide variety of cancers including those of the urinary bladder, breast
Categories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalHydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Synonyms: N-Hydroxyurea, N-CarbamoylhydroxylamineCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsAlvespimycin
go.drugbank.com/drugs/DB12442InvestigationalAlvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.
Adakitug
go.drugbank.com/drugs/DB05484InvestigationalMDX-018, also known as HuMax-Inflam, is a fully human antibody that is directed to IL-8 (interleukin-8) and may have potential application in oncology and inflammation. … Trials will initially focus on studies to treat glioblastoma, a cancer of the central nervous system.
Synonyms: HuMax IL-8, HuMax-IL-8Poliovirus type 1 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10795ApprovedInvestigationalThe vaccine contains purified and inactivated poliovirus type 1 that were grown from a continuous line of monkey kidney cells. … Poliovirus type 1 antigen is a suspension of poliovirus Type 1 (Mahoney) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis
Synonyms: Inactivated poliovirus type I, poliovirus vaccine inactivated, type 1 (Mahoney)Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, PENTAXİM 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇİN TOZ İÇEREN FLAKON VE SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETPoliovirus type 3 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10797ApprovedInvestigationalThe vaccine contains purified and inactivated poliovirus type 3 that were grown from a continuous line of monkey kidney cells. … Poliovirus type 3 antigen is a suspension of poliovirus Type 3 (Saukett) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis
Synonyms: poliovirus vaccine inactivated, type 3 (Saukett), Poliovirus type 3 antigen (formaldehyde inactivated)Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, PENTAXİM 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇİN TOZ İÇEREN FLAKON VE SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETMaxy-G34
go.drugbank.com/drugs/DB05718Investigational, while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein. … MAXY-G34 is a pegylated variant of human granulocyte-colony stimulating factor (G-CSF).
Categories: Compounds used in a research, industrial, or household settingCNS-5161
go.drugbank.com/drugs/DB05824ExperimentalCNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.
Cetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). … GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle.
Products: CETROTIDE® 0.25MG, CETROTIDE 3 MG.