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Racemethionine
go.drugbank.com/drugs/DB13972ApprovedA preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% EPhenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnIt also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis.
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedionePiperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedIt has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. … Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist.
Mixtures: R & C Shampoo With Conditioner, KWELL-P %0,3 + %3 MEDİKAL ŞAMPUAN, 60 MLCategories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 1-RingCedazuridine
go.drugbank.com/drugs/DB15694ApprovedInvestigationalAstex Pharmaceuticals Inc under the name INQOVI®. … Myelodysplastic syndromes (MDS) are a group of hematopoietic neoplasms that give rise to variable cytopenias progressing to secondary acute myeloid leukemia (sAML), which is invariably fatal if untreated
Synonyms: (4R)-2'-Deoxy-2',2'-difluoro-3,4,5,6-tetrahydrouridineCategories: Heterocyclic Compounds, 1-RingHuman botulinum neurotoxin A/B immune globulin
go.drugbank.com/drugs/DB14115ApprovedInfant botulism is a rare infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. … to more serious symptoms such as respiratory arrest and flaccid paralysis.
Synonyms: Human botulinum neurotoxin A/B immune globulinCategories: Human Immunoglobulin GClenbuterol
go.drugbank.com/drugs/DB01407ApprovedInvestigationalVet approvedA substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Mixtures: BRONCOCHEM® F JARABE ADULTOS, BRONCOCHEM® F JARABE ADULTOSCategories: Agents to Treat Airway Disease, Cytochrome P-450 SubstratesTelaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnHCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … Telaprevir was available as a fixed dose product (tradename Incivek) used for the treatment of chronic Hepatitis C.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamidePemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnAs an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. … Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
Categories: Heterocyclic Compounds, 1-RingLumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigationalSchizophrenia is a complex mental illness and impacts approximately 1% of the population. … [A189093,A189174] The data so far indicates that lumateperone can alleviate both positive and negative symptoms of schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesPonesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079] Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to be responsible for a portion of it's adverse effects, and so more selective modulators were developed. … Ponesimod is a selective sphingosine 1-phosphate receptor 1 modulator indicated in the treatment of relapsing forms of multiple sclerosis in adults.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates