Racemethionine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Racemethionine
DrugBank Accession Number
DB13972
Background

A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.

Type
Small Molecule
Groups
Approved, Experimental
Structure
Weight
Average: 149.211
Monoisotopic: 149.051049291
Chemical Formula
C5H11NO2S
Synonyms
  • (+-)-Methionine
  • DL-Methionine
  • DL-Methioninum
  • metionina
  • Racemethionine

Pharmacology

Indication

Not Available

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Associated Therapies
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
24 Multivitamins + MineralsRacemethionine (25 mg) + Ascorbic acid (150 mg) + Beta carotene (10000 unit) + Biotin (25 mcg) + Calcium (130 mg) + Cholecalciferol (400 unit) + Choline bitartrate (25 mg) + Chromium (20 mcg) + Copper (1 mg) + Cyanocobalamin (25 mcg) + Ferrous fumarate (15 mg) + Folic acid (.8 mg) + Inositol (25 mg) + Magnesium (65 mg) + Manganese (2 mg) + Molybdenum (20 mcg) + Niacin (25 mg) + Calcium pantothenate (25 mg) + Potassium (15 mg) + Potassium Iodide (.1 mg) + Pyridoxine hydrochloride (25 mg) + Riboflavin (25 mg) + Selenium (20 mcg) + Thiamine hydrochloride (25 mg) + Vanadium (20 mcg) + Vitamin A palmitate (5000 unit) + Vitamin E (50 unit) + Zinc (10 mg)TabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-04-302002-07-31Canada flag
50 PlusRacemethionine (20 mg) + Ascorbic acid (200 mg) + Biotin (20 mcg) + Choline bitartrate (20 mg) + Cyanocobalamin (20 mcg) + Folic acid (.2 mg) + Inositol (20 mg) + Niacin (20 mg) + Calcium pantothenate (20 mg) + Pyridoxine hydrochloride (20 mg) + Riboflavin (20 mg) + Thiamine hydrochloride (20 mg) + Vitamin A palmitate (10000 unit) + Vitamin D (400 unit) + Vitamin E (20 unit)TabletOralQuest Vitamins A Div Of Purity Life Health Products1998-08-042001-07-06Canada flag
8.5% Freamine IIIRacemethionine (450 mg / 100 mL) + Alanine (600 mg / 100 mL) + Arginine (810 mg / 100 mL) + Cysteine hydrochloride (13.9 mg / 100 mL) + Glycine (1.19 g / 100 mL) + Histidine (240 mg / 100 mL) + Isoleucine (590 mg / 100 mL) + Leucine (770 mg / 100 mL) + Lysine acetate (620 mg / 100 mL) + Phenylalanine (480 mg / 100 mL) + Proline (950 mg / 100 mL) + Serine (500 mg / 100 mL) + Threonine (340 mg / 100 mL) + Tryptophan (130 mg / 100 mL) + Valine (560 mg / 100 mL)LiquidIntravenousB. Braun Medical Inc.1999-05-172012-04-16Canada flag
A/o-26 - CapletRacemethionine (50 mg) + Beta carotene (7500 unit) + Calcium (75 mg) + Calcium ascorbate (250 mg) + Copper (1 mg) + DL-alpha tocopheryl acetate (100 unit) + Folic acid (.4 mg) + Manganese (2.5 mg) + Selenium (100 mcg) + Zinc (7.5 mg)TabletOralEnviro Tech International Canada1996-12-191999-07-26Canada flag
Amino-cervRacemethionine (0.83 %) + Cystine (0.354 %) + Inositol (0.83 %) + Sodium propionate (0.50 %) + Urea (8.34 %)CreamVaginalMilex, A Coopersurgical Co.1952-12-312007-07-26Canada flag
AMINOPLASMAL® 10% ERacemethionine (4.4 g) + Alanine (10.5 g) + Arginine (11.5 g) + Aspartic acid (5.6 g) + Glutamic acid (7.2 g) + Glycine (12 g) + Histidine (3 g) + Isoleucine (5 g) + Leucine (8.9 g) + Lysine hydrochloride (8.56 g) + Magnesium chloride hexahydrate (0.508 g) + Phenylalanine (4.7 g) + Potassium acetate (2.453 g) + Proline (5.5 g) + Serine (2.3 g) + Sodium acetate trihydrate (2.858 g) + Sodium hydroxide (0.36 g) + Sodium phosphate, dibasic dodecahydrate (3.581 g) + Threonine (4.2 g) + Tryptophan (1.6 g) + Tyrosine (0.4 g) + Valine (6.2 g)SolutionIntravenousB. BRAUN MEDICAL S.A.2015-07-27Not applicableColombia flag
AMINOPLASMAL® B. BRAUN 10%Racemethionine (4.4 g) + Alanine (10.5 g) + Arginine (11.5 g) + Aspartic acid (5.6 g) + Glutamic acid (7.2 g) + Glycine (12 g) + Histidine (3 g) + Isoleucine (5 g) + Leucine (8.9 g) + Lysine acetate (5.74 g) + Lysine (3.12 g) + Phenylalanine (4.7 g) + Proline (5.5 g) + Serine (2.3 g) + Threonine (4.2 g) + Tryptophan (1.6 g) + Tyrosine (0.4 g) + Valine (6.2 g)Solution, concentrateIntravenousB BRAUN MEDICAL S.A2015-08-31Not applicableColombia flag
Aminoven 15 % - InfusionslösungRacemethionine (0.38 g) + Alanine (2.5 g) + Arginine (2 g) + Glycine (1.85 g) + Histidine (0.73 g) + Isoleucine (0.52 g) + Leucine (0.89 g) + Lysine acetate (1.566 g) + Phenylalanine (0.55 g) + Proline (1.7 g) + Serine (0.96 g) + Taurine (0.2 g) + Threonine (0.86 g) + Tryptophan (0.16 g) + Tyrosine (0.04 g) + Valine (0.55 g)SolutionParenteralFresenius Kabi Austria Gmb H1999-10-22Not applicableAustria flag
AMINOVEN® 15 %Racemethionine (0.38 g) + Alanine (2.5 g) + Arginine (2 g) + Glycine (1.85 g) + Histidine (0.73 g) + Isoleucine (0.52 g) + Leucine (0.89 g) + Lysine acetate (1.566 g) + Phenylalanine (0.55 g) + Proline (1.7 g) + Serine (0.96 g) + Taurine (0.2 g) + Threonine (0.86 g) + Tryptophan (0.16 g) + Tyrosine (0.04 g) + Valine (0.55 g)SolutionIntravenousFresenius Kabi Austria GmbH2006-11-10Not applicableColombia flag
Body Tropics Plus TabRacemethionine (100 mg) + Bromelains (50 mg) + Choline bitartrate (500 mg) + Inositol (250 mg) + Pyridoxine (25 mg)TabletOralPro Shop Inc.1994-12-312008-08-02Canada flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
73JWT2K6T3
CAS number
59-51-8
InChI Key
FFEARJCKVFRZRR-UHFFFAOYSA-N
InChI
InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
IUPAC Name
2-amino-4-(methylsulfanyl)butanoic acid
SMILES
CSCCC(N)C(O)=O

References

General References
Not Available
Human Metabolome Database
HMDB0033951
KEGG Drug
D04983
KEGG Compound
C01733
ChemSpider
853
BindingDB
86195
RxNav
9100
ChEBI
16811
ChEMBL
CHEMBL274119
Wikipedia
Methionine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidIntravenous
CreamVaginal
SolutionIntravenous
Solution, concentrateIntravenous
CapsuleOral
TabletOral
LiquidOral
EmulsionIntravenous0.468 g
Tablet, extended releaseOral
EmulsionParenteral
EmulsionIntravenous
EmulsionIntravenous4 g
SolutionIntravenous434 mg
SolutionParenteral
Tablet, sugar coatedOral
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility23.9 mg/mLALOGPS
logP-1.8ALOGPS
logP-2.2Chemaxon
logS-0.8ALOGPS
pKa (Strongest Acidic)2.53Chemaxon
pKa (Strongest Basic)9.5Chemaxon
Physiological Charge0Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area63.32 Å2Chemaxon
Rotatable Bond Count4Chemaxon
Refractivity37.59 m3·mol-1Chemaxon
Polarizability15.61 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-004i-0900000000-c74bbe6da11b7c8f48f8
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0a4i-0950000000-ce063fd901edea1f6f81
Mass Spectrum (Electron Ionization)MSsplash10-08ir-9200000000-99eac412c38ff09dedc2
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-2900000000-67e023372cdbac09cb36
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-0udi-9800000000-1e589df1b14865d84d74
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-056r-9000000000-efb0cddabddaf5231dbd
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-0002-6900000000-9ef89c92bce71adb0b81
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-0002-9300000000-8507980760c8afb7f454
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-0002-9000000000-544c2c943904dcca737e
LC-MS/MS Spectrum - LC-ESI-IT , negativeLC-MS/MSsplash10-0udi-1900000000-ce17a3e11ac74608abf5
MS/MS Spectrum - , negativeLC-MS/MSsplash10-0002-1900000000-c965767347d7c1622965
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0udi-0900000000-c9263687f6e32445137a
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0udi-1900000000-83702a37901ca71b058c
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-0zfr-9800000000-9f63601c65b44c2e05da
LC-MS/MS Spectrum - LC-ESI-QTOF , positiveLC-MS/MSsplash10-08fr-9000000000-56a9aa89915835ec0897
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-001i-0900000000-a048656aba28bbb0d512
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-001i-0900000000-cfa6fd6d4117ae7059c3
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0udi-0900000000-490e68b186cda555b7d3
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-0900000000-2191bd36a8f292c32048
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-001i-0900000000-a8e6fe85bb6f29913a51
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-0910000000-071f595c8b078081b359
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-0900000000-efe1cbd495dd26a50289
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-0900000000-1aad026814aaabf843ef
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-0900000000-cf96556b080c962000d9
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0f89-1900000000-d03cf3d65f8ae64087f9
LC-MS/MS Spectrum - LC-ESI-ITFT , positiveLC-MS/MSsplash10-0udi-0900000000-b2b15d90a670baea5490
MS/MS Spectrum - , positiveLC-MS/MSsplash10-0udi-3900000000-d0af3c89f9d94853572f
13C NMR Spectrum1D NMRNot Applicable

Drug created at January 17, 2018 22:23 / Updated at October 20, 2021 17:29