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Propanoic acid
go.drugbank.com/drugs/DB03766ApprovedInvestigationalVet approvedWithdrawnIt is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. … Sodium propionate was previously approved in Canada as an active ingredient in Amino-Cerv (used to treat inflammation or injury of the cervix).
Natural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalOther techniques involve using umbilical cord blood (UCB) directly; these NK cells have heterogeneous CD56 expression but are considered suitable for immunotherapy. … It is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells.
Synonyms: NK CellsBlood Transfusion Complications
go.drugbank.com/conditions/DBCOND0086922Synonyms: Dyspnea due to and following transfusion, Dyspnoea due to and following transfusionMirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigational[L46252] It was officially approved in the EU in May 2023[L48656] and Canada in July 2023[L48661], and was eventually approved in the US in October 2023[L48651] for the treatment of adult patients with … Mirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAlosetron
go.drugbank.com/drugs/DB00969ApprovedWithdrawnAlosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes.
Categories: Alimentary Tract and MetabolismExacerbation of asthma
go.drugbank.com/conditions/DBCOND0022084Synonyms: Other and unspecified asthmaPozelimab
go.drugbank.com/drugs/DB15218ApprovedInvestigationalCD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. … [A261115] The loss of CD55 can therefore induce complement hyperactivation, causing the unwanted formation of membrane-attacking complex and resulting in paroxysmal nocturnal hemoglobinuria and complement-mediated
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsDonidalorsen
go.drugbank.com/drugs/DB18751ApprovedInvestigational[L53788] Donidalorsen was approved by the FDA in August 2025 for prophylactic use to prevent HAE attacks.[L53783,L53788] It is the first RNA-targeted therapy approved for HAE.[L53783] … [A274308] Donidalorsen is a ligand-conjugated antisense oligonucleotide that reduces plasma prekallikrein production, thereby reducing bradykinin production and preventing the initiation of attacks.
Categories: Drugs Used in Hereditary Angioedema, Nucleic Acids, Nucleotides, and NucleosidesVenous Thromboembolism
go.drugbank.com/conditions/DBCOND0000676Drugs: Acetylsalicylic acid · Betrixaban · Dabigatran etexilate · Dalteparin · Nadroparin · Rivaroxaban +1 moreSynonyms: Acute embolism and thrombosis of unspecified veinJoint sprains
go.drugbank.com/conditions/DBCOND0101640Drugs: EscinSynonyms: (Sprains and strains NOS) or (sprain: [joint NOS] or [ligament NOS] or [muscle NOS] or [rectus sprain] or [tendon NOS]) or (tendon rupture NOS)