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Displaying results 3171 - 3180 of 6951 in total
  1. Target

    Nischarin

    go.drugbank.com/bio_entities/BE0003580
    TargetHumans

    Acts either as the functional imidazoline-1 receptor (I1R) candidate or as a membrane-associated mediator of the I1R signaling.

    Synonyms: Imidazoline receptor 1, Imidazoline-1 receptor
  2. Drug

    TMC-310911

    go.drugbank.com/drugs/DB15623
    Investigational

    [L12045] It is being investigated for use in HIV-1 infections. … [L12045,A191643] TMC-310911 is currently being investigated, in combination with other HIV therapies and antivirals, as a potential treatment for COVID-19 caused by SARS-CoV-2.[L12012]

    Categories: Antivirals for Systemic Use, Experimental Unapproved Treatments for COVID-19
  3. Drug

    Progabide

    go.drugbank.com/drugs/DB00837
    Experimental

    It has agonistic activity for both the GABAA and GABAB receptors. … In clinical trials, progabide has been investigated for Parkinson's disease, schizophrenia, clinical depression and anxiety disorder; its therapeutic effectiveness in these conditions is not fully elucidated

  4. Drug

    Difluocortolone

    go.drugbank.com/drugs/DB09095
    ApprovedWithdrawn

    It is commonly used in dermatology for the reduction of inflammation and itching. It was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.[L1082]

  5. Drug

    Altropane

    go.drugbank.com/drugs/DB04947
    Investigational

    Boston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and

  6. Drug

    LX201

    go.drugbank.com/drugs/DB04943
    Investigational

    The implant is being developed clinically for the prevention of rejection in corneal transplantation. It is being developed by Lux Biosciences, Inc.

  7. Drug

    Acitretin

    go.drugbank.com/drugs/DB00459
    ApprovedInvestigational

    An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

    Categories: Antipsoriatics for Systemic Use, Retinoids for Treatment of Psoriasis
  8. Drug

    Tirapazamine

    go.drugbank.com/drugs/DB04858
    Investigational

    Tirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological cancer, as well as for other solid tumor cancer types. … For all these reasons, the combination of tirapazamine with other anticancer treatments is highly recommended.

  9. Drug

    Cyclothiazide

    go.drugbank.com/drugs/DB00606
    Approved

    As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibi...

  10. Drug

    NP2

    go.drugbank.com/drugs/DB06308
    Investigational

    It was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain).