Search

Displaying results 3171 - 3180 of 8517 in total
  1. Drug

    Temocillin

    go.drugbank.com/drugs/DB12343
    ApprovedInvestigationalWithdrawn

    Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.

  2. Drug

    Cyproheptadine

    go.drugbank.com/drugs/DB00434
    ApprovedInvestigational

    Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in ...

  3. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    Gimeracil is an adjunct to antineoplastic therapy, used to increase the concentration and effect of the main active componets within chemotherapy regimens. Approved by the European Medicines Agency (EMA) in March 2011, Gimeracil is avail...

  4. Drug

    Methylprednisone

    go.drugbank.com/drugs/DB12952
    ApprovedInvestigationalWithdrawn

    Methylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.

  5. Drug

    Diaminopropanol tetraacetic acid

    go.drugbank.com/drugs/DB12362
    ApprovedWithdrawn

    Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.

  6. Drug

    Chlormezanone

    go.drugbank.com/drugs/DB01178
    ApprovedWithdrawn

    It has been suggested for use in the treatment of muscle spasm.

  7. Drug

    Tirapazamine

    go.drugbank.com/drugs/DB04858
    Investigational

    This activation is very useful as this hypoxic state is found in human solid tumors in a common phenomenon known as tumor hypoxia. … Tirapazamine entered phase III testing in 2006 for patients with head and neck cancer and gynecological cancer, as well as for other solid tumor cancer types.

  8. Drug

    Filgotinib

    go.drugbank.com/drugs/DB14845
    ApprovedInvestigational

    [A189165] New therapeutic developments target other inflammatory pathways implicated in RA including the Janus kinase (JAK) signaling pathway as seen with filgotinib.

  9. Drug

    Pegzilarginase

    go.drugbank.com/drugs/DB14780
    Approved

    Pegzilarginase is a recombinant, cobalt-substituted, and pegylated human arginase 1 enzyme therapy designed to address the underlying metabolic deficit in arginase 1 deficiency (ARG1-D). By substituting the native manganese cofactor with...

  10. Drug

    Aprobarbital

    go.drugbank.com/drugs/DB01352
    ExperimentalIllicit

    Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. … It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment indicated for the use of aprobarbital was subsequently insomnia.