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Ethyl chloride
go.drugbank.com/drugs/DB13259ApprovedWithdrawnIt is still used in the treatment of cellulose to make ethylcellulose for commercial products. Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp.
Metandienone
go.drugbank.com/drugs/DB13586ApprovedWithdrawnIt was introduced to the market in the 1960s but later discontinued and withdrawn from the market. … Although it is prohibited in and outside competition by the World Anti-Doping Agency, metandienone continues to be marketed and misused as a performance-enhancing drug in sports.
Zilganersen
go.drugbank.com/drugs/DB18161ApprovedInvestigationalZilganersen is a glial fibrillary acidic protein (GFAP)-directed antisense oligonucleotide used to treat Alexander disease. … [L64096] Alexander disease is caused by variants in the *GFAP* gene that lead to overproduction and toxic accumulation of GFAP in astrocytes, and dysfunction in astrocytes can over time damage neurons
Chlormerodrin
go.drugbank.com/drugs/DB00534ApprovedWithdrawnIt is no longer used and has been replaced with new classes of diuretic drugs.
Trioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnIn research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage.[3] The compound is has been explored for development of antisense oligonucleotides that can be … cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.
Anistreplase
go.drugbank.com/drugs/DB00029ApprovedWithdrawnA p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins.
Polyquaternium-10 (400 cps at 2%)
go.drugbank.com/drugs/DB11356ApprovedIt is commonly found in cosmetics and personal care products to mainly reduce static electricity and form films.
Iclepertin
go.drugbank.com/drugs/DB19058InvestigationalIclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).
Bronopol
go.drugbank.com/drugs/DB13960ApprovedCompared to other aliphatic halogen-nitro compounds, bronopol is more stable to hydrolysis in aqueous media under normal conditions [A32792].
Cinitapride
go.drugbank.com/drugs/DB08810InvestigationalCinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome