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Phylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigational[A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity
Thalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnIt has been reintroduced and used for a number of inflammatory disorders and cancers.
Fluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalIt is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.
IR501
go.drugbank.com/drugs/DB06464ExperimentalIt specifically targets autoreactive T-cells, reducing their activity. It was last known to be in phase III clinical trials.
Beta-D-Glucose
go.drugbank.com/drugs/DB02379InvestigationalIt is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Lucanthone
go.drugbank.com/drugs/DB04967InvestigationalIt is currently being tested as a radiation sensitizer. … One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46).
Formebolone
go.drugbank.com/drugs/DB01569IllicitInvestigationalIt is on the list of substances prohibited by the Word Anti-Doping Agency, and is regularly screened for in athletes. … It has been used experimentally in the treatment of growth retardation, and has been noted to increase bone mass.
Vilzemetkib
go.drugbank.com/drugs/DB21704ExperimentalThe usage of the INN stem '-metkib' in the name indicates that Vilzemetkib is a MET (mesenchymal epithelial transition factor) kinase inhibitor.
Mubodina
go.drugbank.com/drugs/DB17616ExperimentalIt is a recombinant human minibody directed against complement component C5. … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
PN0621
go.drugbank.com/drugs/DB05218ExperimentalIt targets tumour necrosis factor (TNF) to treat auto-immune inflammatory diseases such as rheumatoid arthritis. It is being developed by Peptech.