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Rituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalFDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label]. … Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes.
Categories: CHOP-R chemotherapy regimenProducts: MABTHERA ® CONCENTRADO DE SOLUCIÓN PARA INFUSIÓN 500 MG / 50 ML, NOVEX 500 MG/50 ML I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE, 1 FLAKONSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[L39267] Sirolimus was also investigated in other cancers such as skin cancer, Kaposi’s Sarcoma, cutaneous T-cell lymphomas, and tuberous sclerosis. … Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria _Streptomyces hygroscopicus_, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: LIKMUN-E, RAPAMUNE ORAL SOLUTION 1 mg/mlTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigationalTestosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position. … [L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Nebido 1000 mg/4 ml Injektionslösung, Testomed 1000 mg/4 ml InjektionslösungTamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigationalTamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations. … [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine, (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylaminePhenol
go.drugbank.com/drugs/DB03255ApprovedInvestigationalAdditionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process termed phenolization. … Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores.
Mixtures: DİŞİNOL 2 G + 0,5 G + 3,5 G/10 ML ÇÖZELTİ, COOLING 5 PLUSCategories: Compounds used in a research, industrial, or household settingSalmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Products: MIACALCIC 100 IU AMPUL, 5 ADET, MIACALCIC INJECTION 50 iu/mlJosamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Synonyms: leucomycin V 3-acetate 4B-(3-methylbutanoate), leucomycin V 3-acetate 4β-(3-methylbutanoate)Products: Josalid 250 mg/5 ml - Saft für Kinder, Josalid 375 mg/5 ml - Saft für KinderFremanezumab
go.drugbank.com/drugs/DB14041ApprovedInvestigationalFremanezumab is a humanized monoclonal antibody targeted against human calcitonin gene-related peptide (CGRP) for the prevention of migraine headaches. … [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and the oral CGRP antagonist [ubrogepant], fremanezumab represents an important step forward in the treatment
Products: AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET, AJOVY 225 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETPasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)Captopril
go.drugbank.com/drugs/DB01197ApprovedInvestigationalATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: CAPOZIDE 50/25 MG TABLETAS, CAPTOPRIL E IDROCLOROTIAZIDE HEXALCategories: P-glycoprotein inhibitors, Agents Acting on the Renin-Angiotensin System