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Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ORLISTAT 120 MG, FINOBES ® 120 MG.Triamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.
Mixtures: Aureocort 1 mg/g + 30 mg/g Salbe, Mlp A-2Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigational[A177577, A177580] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread. … [A177571] Rapid discontinuation of PPIs such as esomeprazole may cause a rebound effect and a short term increase in hypersecretion.
Mixtures: OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA, OCAM PROTECT 15 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the … As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties.
Mixtures: Tylotus Night 325 mg+5 mg+12,5 mg/15 mL Oral Çözelti, Au Kah Chuen FugicalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalsuperficial punctate keratitis and subjective symptoms of discomfort, including pain, burning or pricking, or a tingling sensation after instillation into the cul‐de‐sac. … Intravenous indometacin is administered to close a hemodynamically significant patent ductus arteriosus, as indicated by clinical evidence, in premature infants.
Mixtures: INDOBIOTIC GOZ DAMLASI, 5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalThe enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET, LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 1 ADETRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
Mixtures: DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADETProducts: RAMIPRIL DR. REDDY'S, Ag-ramiprilAcheta domesticus
go.drugbank.com/drugs/DB10866ApprovedHouse cricket allergenic extract is used in allergenic testing.
Synonyms: Acheta domesticusZonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalZonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures. … [L42530,L42535] Zonisamide represents an alternative for patients that remain refractory to established antiepileptic drugs. In 1989, it was approved for commercial use in Japan.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household settingSynonyms: Benzo[d]isoxazol-3-yl-methanesulfonamidePeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalPeppermint oil is used as a flavouring agent in foods and fragrance in hygienic or cosmetic products, and as an anti-itch and cooling agent in topical pharmaceutical products. … There are various over-the-counter and commercial uses of peppermint oil due to its carminative, cholagogue, antibacterial, secretolytic, and choleretic actions [A33056].
Mixtures: MENTOSEPTOL GARGARA, 100 ML, Cal Mo Dol OntCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A Inhibitors