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Displaying results 311 - 320 of 8389 in total
  1. Drug

    Aztreonam

    go.drugbank.com/drugs/DB00355
    ApprovedInvestigational

    A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinf...

    Products: AZACTAM FOR INJECTION 1 g/vial
  2. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).

    Mixtures: Triumeq PDCategories: P-glycoprotein substrates
  3. Drug

    Panax ginseng fruit

    go.drugbank.com/drugs/DB14261
    Investigational

    It is not an approved drug.

    Products: Ginseng Khan, Korea Gongjin-Dan
  4. Drug

    Amifostine

    go.drugbank.com/drugs/DB01143
    ApprovedInvestigational

    A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.

    Products: Ethyol - Pws IV 500mg/vial
  5. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: RIVAROXABAN DR. REDDY'S, Ag-rivaroxaban
  6. Drug

    Brentuximab vedotin

    go.drugbank.com/drugs/DB08870
    ApprovedInvestigational

    In January 2012, the drug label was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and death due to opportunistic JC virus infection post-treatment. … Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL
  7. Drug

    Mestranol

    go.drugbank.com/drugs/DB01357
    ApprovedWithdrawn

    The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.

    Categories: Ethinyl Estradiol, Estradiol Congeners
  8. Drug

    Tinzaparin

    go.drugbank.com/drugs/DB06822
    ApprovedInvestigational

    LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin. … It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally.

    Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INYECTABLE VIAL 2 ML. 20.000 UI/ML.
  9. Drug

    Velaglucerase alfa

    go.drugbank.com/drugs/DB06720
    Approved

    Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also be...

    Products: VPRIV POWDER FOR SOLUTION FOR INFUSION 400 UNITS/VIAL
  10. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or t...

    Mixtures: Refresh Optive Single Vial, Refresh Digital PFProducts: Restore Plus Single Vial, Meijer Lubricant Single Vial