Carboxymethylcellulose is a compound used as an ophthalmic lubricant. Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.
- Mechanism
- Curator reviewed · 3 references
Carboxymethylcellulose binds to the surface of corneal epithelial cells via its glucopyranose subunits binding to glucose receptors GLUT-1. The residence time of carboxymethylcellulose bound to corneal cells is approximately 2 hours as indicated by a short-term binding assay. Binding of carboxymethylcellulose to the matrix proteins stimulated corneal epithelial cell attachment, migration, and re-epithelialization of corneal wounds.
- Primary indication
- Indicated for the symptomatic relief of burning, irritation and discomfort of the eyes due to dryness or exposure to wind or sun.Curator reviewed · 4 structured indications
- First approval
- Canada, 2008
- Also known as
- Carbose · Carboxy methyl cellulose · Carboxymethyl cellulose · Carmellose · Cellulose carboxymethyl ether
- Brand names
Resolves to
What you can answer from here — as of July 17, 2026
Which drugs share a target with Carboxymethylcellulose, and which of those have an active Phase 3 trial?
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