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Displaying results 3191 - 3200 of 7284 in total
  1. Drug

    Nurandociguat

    go.drugbank.com/drugs/DB21720
    Investigational

    Nurandociguat has a monoisotopic molecular weight of 571.25 Da. … Nurandociguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Nurandociguat is a guanylate cyclase activator and stimulator.

  2. Drug

    Talogreptide mesaroxetan

    go.drugbank.com/drugs/DB21743
    Experimental

    Talogreptide mesaroxetan has a monoisotopic molecular weight of 1769.07 Da. … Talogreptide mesaroxetan is a small molecule drug. The usage of the INN stem '-xetan' in the name indicates that Talogreptide mesaroxetan is a chelating agent.

  3. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

    go.drugbank.com/bio_entities/BE0000089
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-15 kDa
  4. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623] … [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.

    Products: LETROZOL 1A PHARMA 2.5MG
  5. Drug

    Omacetaxine mepesuccinate

    go.drugbank.com/drugs/DB04865
    ApprovedInvestigationalWithdrawn

    Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies … Then in March 2006, it received Orphan Drug status from the FDA for the treatment of CML.

    Synonyms: mepesuccinato de omacetaxina, 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
  6. Drug

    Ferric pyrophosphate citrate

    go.drugbank.com/drugs/DB13995
    Approved

    [L1419] It is also FDA approved since 2015.[FDA label] … Ferric pyrophosphate citrate is a soluble iron replacement product.

  7. Drug

    Zopapogene imadenovec

    go.drugbank.com/drugs/DB24672
    ApprovedInvestigational

    Food and Drug Administration (FDA) for the treatment of adults with RRP, receiving full FDA approval on August 15, 2025.[L54081] … [L54081] Zopapogene imadenovec is a non-replicating adenoviral vector–based immunotherapy that expresses a fusion antigen from selected regions of HPV-6/11 proteins to elicit an immune response in RRP.

    Synonyms: human cytomegalovirus (CMV) promoter and terminated with a 3' untranslated region and a simian virus 40 (SV40) polyadenylation signal, DNA (recombinant replication-deficient Gorilla gorilla gorilla adenovirus strain GC4 vector PRGN-2012 human cytomegalovirus promoter plus human papillomavirus 6/11 E2, E4, E6, E7 protein 11 epitope-containing
  8. Drug

    Oxyphenisatin acetate

    go.drugbank.com/drugs/DB14627
    ApprovedWithdrawn

    The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942]

  9. Drug

    Fosazepam

    go.drugbank.com/drugs/DB19580
    Experimental

    Fosazepam is a small molecule drug. The usage of the INN stem '-azepam' in the name indicates that Fosazepam is a diazepam derivative. Fosazepam has a monoisotopic molecular weight of 360.08 Da.

  10. Drug

    Fomocaine

    go.drugbank.com/drugs/DB19969
    Experimental

    Fomocaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Fomocaine is a local anaesthetic. Fomocaine has a monoisotopic molecular weight of 311.19 Da.