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Black cohosh
go.drugbank.com/drugs/DB13975ApprovedBlack cohosh (_Actaea racemosa_ or _Cimicifuga racemosa_), a member of the buttercup family, is a perennial plant which native to North America. … [A32542] Results from studies suggest that C. racemosa possesses a central activity instead of a hormonal effect.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalReslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. … IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label].
Categories: Interleukin-5 AntagonistPrussian blue
go.drugbank.com/drugs/DB06783ApprovedPrussian blue is described as a deep blue pigment that is produced when the oxidation of ferrous ferrocyanide salts occurs. … It contains ferric hexacyanoferrate(II) in a cubic lattice crystal structure.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Ferric hexacyanoferrate(II), Iron(III) hexacyanoferrate(II)Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnAminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. … The FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, 1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazoloneSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnSimeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. … Like all NS3/4A inhibitors, simeprevir is a serine protease inhibitor in similarity to [DB08873] and [DB05521] but is classified as a second generation protease inhibitor.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsDiflorasone
go.drugbank.com/drugs/DB00223ApprovedDiflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
International brands: Florone EProducts: Psorcon E, ApexiCon EBisoctrizole
go.drugbank.com/drugs/DB11262ApprovedBisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212]. … It is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays.
Efavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationalEfavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human … a high risk for HIV transmission.
Mixtures: TOLAK ®3 TABLETAS RECUBIERTAS, TOLAK ®3 TABLETAS RECUBIERTASCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnBufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. … The use of bufexamac has been discontinued in Canada and the United States, which may be due to undetermined clinical efficacy and a high prevalence of contact sensitization [A32822].
Categories: Non COX-2 selective NSAIDSSynonyms: 4-Butoxy-N-hydroxybenzeneacetamide, 2-(p-Butoxyphenyl)-acetohydroxamic acidGuanadrel
go.drugbank.com/drugs/DB00226ApprovedGuanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.