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Acetophenazine
go.drugbank.com/drugs/DB01063ApprovedIt is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Solithromycin
go.drugbank.com/drugs/DB09308InvestigationalSolithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAK119
go.drugbank.com/drugs/DB16423InvestigationalAK119 is a humanized anti-CD73 monoclonal antibody being investigated in the clinical trial NCT04516564 (A Study of AK119 (Anti-CD73 Antibody), a Treatment for COVID-19, in Healthy Subjects).[L28315]
Benactyzine
go.drugbank.com/drugs/DB09023ApprovedWithdrawnBenactyzine is no longer widely used in medicine, although it is still a useful drug for scientific research. It does not possess any antihistamine properties.
Efzofitimod
go.drugbank.com/drugs/DB16453InvestigationalEfzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Categories: Experimental Unapproved Treatments for COVID-19Nifurtimox
go.drugbank.com/drugs/DB11820ApprovedInvestigational[L15361] A convenient feature of Bayer's formulation is the ability to divide the scored tablets manually without the need for pill-cutting devices.[L15361] … Chagas disease, caused by a parasite known as Trypanosoma cruzi (T.cruzi), is a vector-transmitted disease affecting animals and humans in the Americas.
Setiptiline
go.drugbank.com/drugs/DB09304ExperimentalSetiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). … In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.
Nabiximols
go.drugbank.com/drugs/DB14011InvestigationalFrom a pharmacological perspective, Cannabis' diverse receptor profile explains its potential application for such a wide variety of medical conditions. … isomer as [DB00470], or in a 1:1 formulation with CBD from purified plant extract as [DB14011].
Paramethadione
go.drugbank.com/drugs/DB00617ApprovedParamethadione is an anticonvulsant in the oxazolidinedione class. It is associated with fetal trimethadione syndrome, which is also known as paramethadione syndrome.
Carbenoxolone
go.drugbank.com/drugs/DB02329ExperimentalIt is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. [PubChem]
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)