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Cephalexin
go.drugbank.com/drugs/DB00567ApprovedInvestigationalVet approved[A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971. … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide.
Synonyms: 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid, (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: L-Keflex2-[3-chloro-6-[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]imino-1-hydroxypyridin-2-yl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide
go.drugbank.com/drugs/DB04722ExperimentalSynonyms: 2-[3-chloro-6-[2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethyl]imino-1-hydroxypyridin-2-yl]-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamideBamocaftor potassium
go.drugbank.com/drugs/DB17863ExperimentalSynonyms: Potassium (Benzenesulfonyl)({[6-(3-{2-[1-(Trifluoromethyl)Cyclopropyl]Ethoxy}-1H-Pyrazol-1-Yl)-2-[(4S)-2,2,4-Trimethylpyrrolidin-1-Yl]Pyridin-3-Yl]Carbonyl})AzanideStreptozocin
go.drugbank.com/drugs/DB00428ApprovedInvestigationalIt is used as an antineoplastic agent and to induce diabetes in experimental animals.
Synonyms: 1-METHYL-1-NITROSO-3-((3R,4R,5S,6R)-2,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3-YL)UREA, 1-METHYL-1-NITROSO-3-((2R,3R,4S,5R)-3,4,5,6-TETRAHYDROXY-1-OXOHEXAN-2-YL)UREACategories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersFobrepodacin
go.drugbank.com/drugs/DB18409ExperimentalSynonyms: N-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl)-1h-benzimidazol-2-yl)urea, Urea, n-ethyl-n'-(6-fluoro-5-(2-(1-methyl-1-(phosphonooxy)ethyl)-5-pyrimidinyl)-7-((2r)-tetrahydro-2-furanyl)-1h-benzimidazol-2-yl)-Hycanthone
go.drugbank.com/drugs/DB14061ExperimentalPotentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Synonyms: 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one, 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-oneCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 3-RingMethyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate
go.drugbank.com/drugs/DB01989ExperimentalSynonyms: Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinate, Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-OmeCadisegliatin
go.drugbank.com/drugs/DB18886InvestigationalCadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).
Synonyms: 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid, [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid(R)-warfarin
go.drugbank.com/drugs/DB08496ExperimentalS-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.
Synonyms: (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-oneCategories: Vitamin K Antagonists, Cytochrome P-450 SubstratesMPT-0L055
go.drugbank.com/drugs/DB17136ExperimentalSynonyms: 4-(((3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino)methyl)-n-3-pyridinylbenzamide, 4-(((3-chloro-1,4-dioxo-1,4 dihydronaphthalen-2-yl)amino)methyl)-n-(pyridine-3-yl)benzamide