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Rapacuronium
go.drugbank.com/drugs/DB04834ApprovedWithdrawnRapacuronium was withdrawn in 2001 in many countries due to risk of fatal bronchospasm.
Isometheptene
go.drugbank.com/drugs/DB06706ApprovedIsometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Racepinephrine
go.drugbank.com/drugs/DB11124ApprovedIt is an active ingredient in oral inhalation over-the-counter products as racepinephrine hydrochloride.
Ecallantide
go.drugbank.com/drugs/DB05311ApprovedIt was discovered by phage display technology [A32017]. … Apart from its FDA and EMA indication, ecallantide has been used off label in the management of nonhistaminergic angioedema, not due to HAE [A32017].
Votucalis
go.drugbank.com/drugs/DB05032InvestigationalIt is a topically delivered small protein that acts as an anti-inflammatory agent.
Valerian
go.drugbank.com/drugs/DB13196ApprovedValerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance. … Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint pain.
Enfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigationalThe clinical development of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics [A188868] and it was first approved for use in the United States in December … [L10836] Enfortumab vedotin was later approved by the European Commission on April 13, 2022.[L42000]
Uric acid
go.drugbank.com/drugs/DB08844InvestigationalAs a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and as such, uric acid acts as an antioxidant. … In one country, Spain, uric acid is an investigational drug in a phase 3 trial studying its effects as an adjunct to alteplase in acute ischemic stroke.
Coral snake (micrurus fulvius) immune globulin antivenin (equine)
go.drugbank.com/drugs/DB13883ApprovedNorth American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutra...
Testolactone
go.drugbank.com/drugs/DB00894ApprovedWithdrawnAn antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Synonyms: (4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bH)-dione