DB08844InvestigationalSmall molecule
Uric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. Normally a small amount of... Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this can lead to gout and formation of kidney stones.
- Mechanism
- Curator reviewed
The exact mechanism of action for uric acid's antioxidant effects have not yet been elucidated.
- Primary indication
- At present (August 2013), there is no approved indication for uric acid.Curator reviewed
- Formula / weight
- C5H4N4O3 · 168.1103 g/mol (avg)
- Also known as
- Lithic acid · Urate
Resolves to
Clinical / RWD
Structure
InChIKey
LEHOTFFKMJEONL-UHFFFAOYSA-NSMILESO=C1NC2=C(N1)C(=O)NC(=O)N2Targets
Transporters
What you can answer from here — as of April 02, 2025
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
3TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Uric acid, and which of those have an active Phase 3 trial?
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