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Displaying results 3241 - 3250 of 3735 in total
  1. Drug

    Orbifloxacin

    go.drugbank.com/drugs/DB11443
    ExperimentalVet approved

    Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  2. Drug

    Selamectin

    go.drugbank.com/drugs/DB11459
    ExperimentalVet approved

    Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in dogs as well as prevent heartworms, fleas, ear ...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  3. Drug

    Dexamethasone isonicotinate

    go.drugbank.com/drugs/DB11487
    ExperimentalVet approved

    Its unintended mineralocorticoid action may cause salt and water retention.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Substrates
  4. Drug

    Melengestrol

    go.drugbank.com/drugs/DB11529
    ExperimentalVet approved

    Melengestrol is a steroidal progestin and antineoplastic agent which was never marketed. An acylated derivative, melengestrol acetate, is used as a growth promoter in animals.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Products: KYBERNIN P, KYBERNIN P 500
  6. Drug

    Rabies immune globulin, human

    go.drugbank.com/drugs/DB11603
    Approved

    IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced rabies vaccine. Persons previo...

    Products: BERIRAB(R) P, BERIRAB P
  7. Drug

    Tocofersolan

    go.drugbank.com/drugs/DB11635
    Approved

    D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis . Cholestasis is the reduction or stoppage of...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Nomegestrol

    go.drugbank.com/drugs/DB11636
    Approved

    Nomegestrol is an ingredient in the EMA-authorised product Zoely.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Voclosporin

    go.drugbank.com/drugs/DB11693
    ApprovedInvestigational

    Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  10. Drug

    Clobetasol

    go.drugbank.com/drugs/DB11750
    ApprovedInvestigationalWithdrawn

    Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.

    Categories: Corticosteroid Hormone Receptor Agonists, Cytochrome P-450 Substrates