Dexamethasone isonicotinate

DB11487ExperimentalVet approvedSmall molecule

Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.

Formula / weight: C₂₈H₃₂FNO₆ · 497.563 g/mol (avg)

Resolves to

Compound

UNII8LGC0BOA71CAS2265-64-7ChEMBLCHEMBL3186453

Clinical / RWD

RxNorm3265

Structure

InChIKeyBQTXJHAJMDGOFI-NJLPOHDGSA-NSMILES[H][C@@]12C[C@@H](C)[C@](O)(C(=O)COC(=O)C3=CC=NC=C3)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C

What you can answer from here — as of April 02, 2025

1,196Drug interactionsStructured to mechanism, not free text

7+ReferencesStructured and connected to the statements they support

Which companies are running trials of Dexamethasone isonicotinate, in which indications and phases, and which of those programs are still active?

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