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Elranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigationalIt is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one … [L47820] Elranatamab was also approved by the European Commission on December 8, 2023.[L50437]
Synonyms: B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB) ANTI-BCMA/ANTI-CD3 BISPECIFIC MAB, IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS MUSCULUS MONOCLONAL DISULFIDE WITH IMMUNOGLOBULINCategories: Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engagerZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approved[A27280, L2082] Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. … Studies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary.
Mixtures: AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass, FERROZINC - G SURUP, 100 MLProducts: ZINC 50 MG., Zinc 50 Mg - TabSalicylic acid
go.drugbank.com/drugs/DB00936ApprovedInvestigationalVet approvedA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.
Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut, REPARİL-GEL N %1 + %5 JEL, 50 GCategories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSPancuronium
go.drugbank.com/drugs/DB01337ApprovedAs a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release. … A bis-quaternary steroid that is a competitive nicotinic antagonist.
Products: BROMURO DE PANCURONIO 4 MG/2 ML, ºPAVULON SOLUCION INYECTABLE 4 MG/2 MLTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigational[A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging … CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells.
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adetDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalIn September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension occurring in infants and neonates. … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.
Synonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideCategories: Arteriolar Smooth Muscle, Agents Acting On, Cytochrome P-450 SubstratesEtilefrine
go.drugbank.com/drugs/DB08985ApprovedWithdrawnEtilefrine is an adrenergic agonist that appears to interact with beta-1 and some alpha-adrenergic receptors. It has been used as a vasoconstrictor agent.
Categories: Compounds used in a research, industrial, or household setting, Adrenergic beta-1 Receptor AgonistsProducts: Effortil 7,5 mg/ml - Tropfen, ETILEFRINACLORHIDRATO 10 MG /MLEmicizumab
go.drugbank.com/drugs/DB13923ApprovedInvestigationalEmicizumab was originated as an improved form of hBS23 and it was approved on November 16, 2017.[A31279, L1016] It was created by Chugai Pharmaceuticals Co. … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X.
Products: HEMLIBRA® 30 MG/ML SOLUCION INYECTABLE, HEMLIBRA® 150 MG/ML SOLUCIÓN INYECTABLELanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigational[L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells. … [A38676] Lanadelumab was approved for use in patients with hereditary angioedema by the FDA in August 2018,[L4537] followed by Health Canada in October 2018[L49226] and the EMA in November 2018.
Categories: Drugs Used in Hereditary AngioedemaProducts: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETPeanut
go.drugbank.com/drugs/DB10553ApprovedPeanut allergenic extract is used in allergenic testing.
Mixtures: PALFORZIA (Level 3), PALFORZIA (Level 3)Products: PALFORZIA (Level 5), PALFORZIA (Level 1)